دانلود کتاب انسداد خون مغز در سلامت و بیماری (۲ جلدی) |
The Blood-Brain Barrier in Health and Disease, 2-Vol, 1ed
Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into the brain. Over the last 25 years, we have witnessed remarkable expansion of our knowledge of the structure, biology, and function of the cerebral endothelium.
In The Blood-Brain Barrier in Health and Disease, Volume 1, international experts discuss basic and new concepts and most recent advances pertaining to the development of the cerebral microvascular system. Subjects include the structure, function, permeability properties, transport mechanisms, and the inherent heterogeneity of the cerebral endothelium; the anatomy and physiological properties of the neurovascular unit; functional aspects of the choroid plexus; and important concepts and advances made over the last two decades that have shaped our understanding of the immunological function of the blood-brain barrier.
This book is intended to serve as a valuable source of basic and advanced information for researchers, students, and clinicians interested in this fast-expanding field and stimulate further research well into the future.
Located at the interface between blood and the brain, the blood-brain barrier is a dynamic permeability barrier formed by a continuous layer of specialized endothelial cells endowed with important permeability, transport, and regulatory functions that both protect the internal milieu of the brain and allow essential nutrients to be transported into the brain. Abnormalities of the blood-brain barrier are increasingly recognized as a key component in the pathogenesis of a range of primary diseases of the brain and the secondary involvement of the brain from pathological processes in other organs.
In The Blood-Brain Barrier in Health and Disease, Volume 2, international experts present comprehensive reviews and research accounts on blood-brain barrier dysfunction in infectious and inflammatory diseases, cerebrovascular diseases, stroke, trauma, vitamin deficiency, exposure to neurotoxicants, primary and metastatic brain tumors, and neurodegenerative diseases.
This book is intended to serve as a guide and reference to basic and advanced information for researchers, students, and clinicians interested in this fast-expanding field and stimulate further research well into the future.
Volume I: Morphology, Biology and Immune Function
۱: Morphological and Functional Properties of the Blood-Brain Barrier
۲: The Human Cerebral Cortex Microvascular System: Development and Composition of the Meningeal and Intracerebral Extrinsic and Intrinsic (Blood-Brain Barrier) Compartments
۳: Heterogeneity of the CNS Microvascular Endothelium
۴: The Neurovascular Unit
۵: The Elusive Multipotent Microvascular Pericyte
۶: Fluid-Forming Function of the Choroid Plexus: What is the Role of Aquaporin-1?
۷: The Expression and Function of ABC Transporters at the Blood-Brain Barrier
۸: The Blood-Brain Barrier and the Immune Privilege of the Central Nervous System
۹: Inflammatory Mediators and the Blood-Brain Barrier
۱۰: Endothelial Surface-Associated Molecules of Relevance to the Immune Function of the Blood-Brain Barrier
۱۱: Chemokines as Mediators of Leukocyte Trafficking and Activation at the Blood-Brain Barrier
۱۲: Leukocyte Entry into the Brain
Volume II: Pathophysiology and Pathology
۱. Blood-Brain Barrier Disruption in Multiple Sclerosis
۲. Portals of Viral Entry into the Central Nervous System
۳. Blood Brain Barrier (BBBJ Dysfunction in HIV Infection
۴. The Brain Microvasculature in Cerebral Malaria
۵. The Blood-Brain Barrier in Bacterial Infections of the Central Nervous System
۶. Blood-Brain Barrier in Fungal Infections of the Central Nervous System
۷. Blood-Brain Barrier Changes in Traumatic Brain Injury
۸. Alterations of the Blood-Brain Barrier in Post-Traumatic Epilepsy
۹. Functional and Molecular Mechanisms of Hypertensive Brain Damage
۱۰. Blood Brain Barrier Protection in Stroke: Taming tPA
۱۱. Radiation-Induced Blood-Brain Barrier Disruption
۱۲. The Blood-Brain Barrier in Thiamine Defi ciency (Wernicke ‘s Encephalopathy)
۱۳. The Blood-Brain-Barrier in Brain Tumors
۱۴. Cerebral Amyloid Angiopathy: Clinicopathologic Features and Pathogenesis
۱۵. Vascular Factors and the Blood Brain Barrier in Alzheimer’s Diseaser Parkinson’s Disease and Amyotrophic Lateral Sclerosis
۱۶. Blood-Brain Barrier Damage in the Context of HIV Infection and Drug Abuse
لینک کوتاه : https://bookbaz.ir/?p=50743
نویسنده : Katerina Dorovini-Zis
ناشر : CRC Press
سال انتشار : 2016
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 808
(ISBN) شابک : 1498727050
قیمت کتاب درآمازون : $159.95
حجم فایل : $159.95