دانلود کتاب تنظیم ژن و درمان سرطان
Gene Regulation and Therapeutics for Cancer, 1ed

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Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.

Review

The book discusses the specific genes that regulate several malignancies and the available and optimized targeted therapies to treat such cancers. This is an excellent book that provides an interesting account on transcriptional dysregulation in cancer and how transcriptional regulation by therapeutic agents serves as a platform to design clinical trials in the questof cures for cancer. It is quite unique in discussing this complex subject matter concisely and clearly.

Omer Iqbal, Loyola University Medical Center

Contents

۱. Programmed Death 1Receptor (PD-l)-mediated Immunomodulatory Effects in Pancreatic Cancer
۲. Nuclear Factor Kappa-B: Bridging Inflammation and Cancer
۳. The S100A7/8/9 Proteins: Novel Biomarker and Therapeutic Targets for Solid Tumor Stroma
۴. Nuclear Receptor Coactivators: Mechanism and Therapeutic Targeting in Cancer
۵. Liquid Biopsies for Pancreatic Cancer: A Step Towards Early Detection
۶. Targeting Subgroup-specific Cancer Epitopes for Effective Treatment of Pediatric Medulloblastoma
۷. Aberrant Methylation of UC Promoters in Human Pancreatic Ductal Carcinomas
۸. Receptor Tyrosine Kinase Signaling Pathways as a Goldmine for Targeted Therapy in Head and Neck Cancers
۹. Molecular Drivers in Lung Adenocarcinoma: Therapeutic Implications
۱۰. Molecular Mediator of Prostate Cancer Progression and Its Implication in Therapy
۱۱. Therapeutic Options for Prostate Cancer: A Contemporary Update
۱۲. Regulation and Targeting of MUCINS in Pancreatic Cancer
۱۳. Targeted Therapy for Cancer Stem Cells

قیمت : 5000 تومان
لینک کوتاه : https://bookbaz.ir/?p=254922
نویسنده : Surinder K. Batra
ناشر : CRC Press; 1st edition
سال انتشار : 2022
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 329
(ISBN) شابک : 1138712426
قیمت کتاب درآمازون : $177.31
حجم فایل : 12 MB

۵۰۰۰ تـومان – خرید