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دانلود کتاب تومور استروما: بیولوژی و درمان
Tumor Stroma: Biology and Therapeutics, 1ed
|
The identification of the role of tumor stroma―the tissue in the surroundings of cancer cells―in cancer development, progression, and metastasis has revolutionized the fields of cancer biology as well as cancer therapeutics. This book provides a comprehensive overview of this rapidly-evolving field including tumor stroma biology, therapeutic targets, molecular imaging, and advanced tumor stroma in vitro models. The book will serve as a handbook for graduate students, postgraduate researchers, pharmaceutical scientists, and biomedical engineers.
About the Author
Jai Prakash, professor of targeted therapeutics and nanomedicine at the University of Twente in the Netherlands, is a pharmaceutical and bioentrepreneurial scientist with a background in developing novel targeted (nano)therapeutics against fibrosis and tumor stroma. He obtained his PhD (cum laude) in 2006 from the University of Groningen, the Netherlands, and thereafter worked as vice president at BiOrion Technologies BV, the Netherlands, assistant professor at Karolinska Institutet, Sweden, and tenure track professor at the University of Twente. He is a founder and CSO of a spin-off company ScarTec Therapeutics BV, the Netherlands, which develops novel therapeutics against fibrosis and cancer. He holds several academic positions, including president of BeNeLux and France local chapter for the Controlled Release Society, and editorial positions for many journals. He is expert referee for more than 20 grant agencies worldwide. His current research focuses on designing targeting technologies to modulate the tumor microenvironment to intervene into the fibrotic and inflammatory crosstalk between tumor cells and stromal cells.
Contents
۱. The Tumor Stroma: Key Component of Solid Tumors
۲. Cancer-Associated Fibroblasts: Building Blocks of the Tumor Stroma
۳. Tumor-Associated Macrophages: Biological Understanding and Therapeutic Opportunities
۴. Biomarkers in the Tumor Stroma and Their Clinical Relevance
۵. Physical Properties of the Tumor Stroma and Therapeutic Strategies
۶. TGF-β Signalling in Cancer: Role and Therapeutic Targeting of the Tumour Stroma
۷. Role of Integrins in the Tumor Stroma
۸. MicroRNA in the Tumor Stroma: Diagnostic and Therapeutic Implications
۹. Molecular Imaging of the Tumor Stroma and Beyond
۱۰. ۳D in vitro Models to Mimic the Tumor Microenvironment
لینک کوتاه : https://bookbaz.ir/?p=263212
نویسنده : Jai Prakash
ناشر : Jenny Stanford Publishing; 1st edition
سال انتشار : 2022
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 446
(ISBN) شابک : 9814968064
قیمت کتاب درآمازون : $244.06
حجم فایل : 20 MB
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