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Molecular and Cellular Therapies for Motor Neuron Diseases, 1ed

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Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians.

Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.

  • Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases
  • Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance
  • Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy

From the Back Cover

Motor Neuron Diseases (MND) are a group of neurological disorders that affect motor neurons in adults and in children. The fields of gene and cell therapies for motor neuron diseases are constantly evolving. Molecular and Cellular Therapies for Motor Neuron Disease discusses the basics of the diseases and covers both advances in research and clinical trials. It gives a resource to students to learn the basics and also provides the details required for scientists and clinicians.

Molecular and Cellular Therapies for Motor Neuron Disease provides a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), and the current understanding of their genetics and mechanisms. Molecular and Cellular Therapies for Motor Neuron Disease also details gene and cell therapies that have been developed and how some of these have been translated to clinical trials.

Contents

Chapter 1. Molecular and Extracellular Cues in Motor Neuron Specification and Differentiation
Chapter 2. Natural History of Amyotrophic Lateral Sclerosis
Chapter 3. Genetics of Amyotrophic Lateral Sclerosis
Chapter 4. Molecular Mechanisms of Amyotrophic Lateral Sclerosis
Chapter 5. An Introduction to the Natural History, Genetic Mapping, and Clinical Spectrum of Spinal Muscular Atrophy
Chapter 6. Genetics of Spinal Muscular Atrophy
Chapter 7. Introduction to Gene and Stem-Cell Therapy
Chapter 8. Gene Therapy for Amyotrophic Lateral Sclerosis: Therapeutic Transgenes
Chapter 9. Stem Cell Therapy for Amyotrophic Lateral Sclerosis
Chapter 10. Gene Therapy for Spinal Muscular Atrophy
Chapter 11. Cellular Therapy for Spinal Muscular Atrophy: Pearls and Pitfalls
Chapter 12. Clinical Trials to Date

قیمت : 3500 تومان
لینک کوتاه : https://bookbaz.ir/?p=110990
نویسنده : Nicholas M Boulis , Deirdre O'Connor
ناشر : Academic Press; 1 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 319
(ISBN) شابک : 0128022574
قیمت کتاب درآمازون : $111.54
حجم فایل : 12 MB

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