دانلود کتاب رادیو حساس کننده ها و رادیو شیمی درمانی در درمان سرطان
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer, 1ed
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range of topics, covering everything from molecular oxygen and high Z elements to monoclonal antibodies and complex phytochemicals.
At the molecular level, the understanding of the molecular consequences of DNA damage and the DNA damage response have informed the development of targeted radiosensitizers and shed light on the mode of action of radiochemotherapy protocols of known clinical efficacy.
In this book the mechanisms of action at the molecular and cellular level are described for documented radiosensitizers including, where applicable, a brief history of their clinical use and most recent clinical results. In addition, the clinical context is addressed including the importance of factors such as dose and dose rate, normal tissue toxicity, and drug delivery. Intuitively organized by topic and application, the book includes extensive illustrations, end-of-chapter summaries, and a wealth of references.
Review
About the Author
Contents
Chapter 1: Radiosensitization and Chemoradiation
Chapter 2: Radiosensitization by Oxygen and Nitric Oxide
Chapter 3: Radioenhancement by Targeting Cellular Redox Pathways and/or by Incorporation of High-Z Materials into the Target
Chapter 4: Radiosensitization by Halogenated Pyrimidines
Chapter 5: Radiosensitization by Antimetabolites
Chapter 6: Radiosensitization by Platinum Drugs and Alkylating Agents
Chapter 7: Topoisomerase Inhibitors and Microtubule-Targeting Agents
Chapter 8: Targeting the DMA Damage Response : ATM, p53r Checkpointsr and the Proteasome
Chapter 9: Radiosensitization by Inhibition of DNA Repair
Chapter 10: Targeting Growth Factor Receptors for Radiosensitization
Chapter 11: Targeting Signaling Molecules for Radiosensitization
Chapter 12: Radiosensitization by Targeting the Tumor Microenvironment
Chapter 13: Phytochemicals : Chemopreventiver Radiosensitizing, Radioprotective
Chapter 14: Delivery Methods for Radioenhancing Drugs
لینک کوتاه : https://bookbaz.ir/?p=56557
نویسنده : Shirley Lehnert
ناشر : CRC Press; 1 edition
سال انتشار : 2015
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 504
(ISBN) شابک : 1439829020
قیمت کتاب درآمازون : $134.23
حجم فایل : 38 MB