دانلود کتاب شیمی درمانی و بیوتراپی سرطان: اصول و تمرین
Cancer Chemotherapy and Biotherapy: Principles and Practice, 5ed

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Updated to include the newest drugs and those currently in development, Cancer Chemotherapy and Biotherapy, Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. Chapters emphasize pharmacology and mechanisms of action at the molecular and cellular levels, followed by clinical activity and toxicity, both acute and delayed. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations.

This edition’s introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised.

A companion website includes the fully searchable text and an image bank.

Features

NEW! Introductory section completely overhauled to include new information on:
— general strategies for drug usage
— the science of drug discovery and development
— economic and regulatory aspects of cancer drug development
— principles of pharmacokinetics
NEW! Eight new chapters added, seven revised with new authors
NEW! Significant overhaul to more than 20 other chapters, especially drug information
–Organized by drug class, not disease
–Illustrates mechanism of action and structure of each drug, as well as its toxicity
–Complete discussion of drug interactions
–Covers all new drugs as well as those in development

Review

New England Journal of Medicine, Volume 18, Issue 355 — “The editors have taken on the Herculean task of melding chemotherapy and biologic therapy, with an emphasis on clinical relevance. To a great degree, they have accomplished their goal. The chapters are up to date, considering the rapid changes in the field. There is extensive use of illustrations and tables, and summary tables in each chapter reinforce the central themes. The discussion of antibody therapy provides an excellent overview of the current state of functional mechanisms. This textbook will continue to be a resource for clinical oncologists, and it remains one of the essential readings for medical oncologists in training. The editors and contributors should be complimented on the results of their labors, which improve on their previous exceptional efforts.” –This text refers to an out of print or unavailable edition of this title.

Contents

۱. Clinical Strategies for Cancer Treatment. The Role of Drugs
۲. Target Identification and Drug Discovery
۳. Clinical Drug Development and Approval for Marketing
۴. Principles of Pharmacokinetics
۵. Special Aspects of Brain Tumor Chemotherapy
۶. Pharmacogenetics
۷. Barriers to Drug Delivery
۸. Antifolates
۹. Fluoro-pyrimidines
۱۰. Cytidine Analogues
۱۱. Purine Analogues
۱۲. Hydroxyurea
۱۳. Antimitotic Drugs
۱۴. Alkylating Agents (Including Methylating Agents)
۱۵. Platinum Analogues
۱۶. Antitumor Antibiotics (Including Bleomycin)
۱۷. Topoisomerase I Inhibitors
۱۸. Topoisomerase II Inhibitors. Anthracyclines
۱۹. Topoisomerase II Inhibitors. Etoposide, Teniposide
۲۰. L-Asparaginase
۲۱. Proteosome Inhibitors
۲۲. HDAC Inhibitors
۲۳. Differentiating Agents (Retinoids)
۲۴. Arsenic Trioxide
۲۵. Monoclonal Antibodies. Discovery & Development
۲۶. Anti-angiogenic Agents (Including MonAB)
۲۷. Anti-EGFR Therapies (Including MonAB)
۲۸. Anti-her 2 Therapies
۲۹. Intracellular Signal Inhibitors (bcr-abl)
۳۰. Signal Transduction Inhibitors in Development
۳۱. Inhibitors of the PI3k Pathway & Mitotic Kinase
۳۲. Interferon and Cytokines
۳۳. Vaccines
۳۴. Adoptive Cellular Therapies
۳۵. Immuno-modulatory Drugs (IMIDS, Anti-CTLA4)
۳۶. Hormonal Therapy of Breast Cancer
۳۷. GNRH Agonists and Anti-Androgens
۳۸. Pain Management in Cancer Patients
۳۹. Colony Stimulating Factors
۴۰. Anti-nausea Medications
۴۱. Bone Loss Modulators
۴۲. Intravenous Access and Catheter Management
۴۳. Monitoring for Late Side Effects of Chemotherapy

قیمت : 6000 تومان
لینک کوتاه : https://bookbaz.ir/?p=53634
نویسنده : Bruce A. Chabner MD , Dan L. Longo MD
ناشر : LWW; Fifth edition
سال انتشار : 2011
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 838
(ISBN) شابک : 1605474312
قیمت کتاب درآمازون : $247.14
حجم فایل : 30 MB

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۶۰۰۰ تـومان – خرید