While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents and therapeutic approaches currently in use or in advanced stages of clinical trials, including biological-based therapies.
The book is unique in providing molecular structures for all anticancer agents, discussing them in terms of history of development, chemistry, mechanism of action, structure–function relationships, and pharmacology. It also provides relevant information on side effects, dosing, and formulation. The authors, renowned scientists in cancer research and drug discovery, also provide up-to-date information on the drug discovery process, including discussions of new research tools, tumor-targeting strategies, and fundamental concepts in the relatively new areas of precision medicine and chemoprevention.
Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies. Its breadth of coverage, clear explanations, and illustrations also make it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, dentistry, nutrition, the biomedical sciences, and related disciplines.
- Summarizes the fundamental causes of cancer, modes of treatment, and strategies for cancer drug discovery
- Brings together a broad spectrum of information relating to the chemistry and pharmacology of all families of anticancer agents and therapies
- Includes up-to-date information on cutting-edge aspects of cancer treatments such as biomarkers, pharmacogenetics, and pharmacogenomics
- Features new chapters on the “Evolution of Anticancer Therapies”, “Antibody-Based Therapies”, and “Cancer Chemoprevention”
“…This text is a gem for any graduate student in the pharmaceutical sciences or for anyone seeking an introductory reference in the area of anticancer drugs.”
— John S. Williamson, University of Mississippi, writing in the Journal of Medicinal Chemistry, Vol. 50, No. 26: December 27, 2007
The author explains in the foreword that this, ‘book attempts to bring together a broad spectrum of information relating to the chemistry and pharmacology of anticancer drugs and therapies.’ The author succeeds in this aim in a very elegant text. The book is both informative and easy to read. It is a very interesting book and would be a welcome addition to any individual’s collection, and essential if this is your field.
– Steve Mitchell, Faculty of Medicine, Imperial College London in Imperial College of Science Technology, July 2008
. . . a noteworthy survey . . . The author, a renowned scientist in cancer research and drug development, clearly does not fail to provide up-to-date information on this trend in today’s pharmacology. A book that covers such a large number of anticancer drugs, ranging from those in clinical use to those under basic research, is nearly impossible to write. Dr. Thurston has done so, however, thanks to his expertise in the field . . . easy readability and directness make the book ideal for students . . . an indispensable resource for the libraries of research institutes, universities, and hospitals.
لینک کوتاه : https://bookbaz.ir/?p=270922
نویسنده : David E. Thurston
ناشر : CRC Press; 2nd edition
سال انتشار : 2021
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 619
(ISBN) شابک : 1138323586
قیمت کتاب درآمازون : $345.10
حجم فایل : 90 MB