دانلود کتاب علوم اعصاب نانو و جراحی مغز و اعصاب نانو
The Textbook of Nanoneuroscience and Nanoneurosurgery, 1ed

Nanoneuroscience, nanoneurosurgery, and nanobioelectronics have the potential to revolutionize medicine and improve the prevention, diagnosis, and treatment of neurological disorders over the next 10-20 years. The Textbook of Nanoneuroscience and Nanoneurosurgery presents a state-of-the-art review of the field, providing current information about nanoplatforms and their use in neurosurgery, neurology, neuroscience, and neuroradiology.

The text also reviews the latest regulatory guidelines that influence the translation of nanotechnological research from the laboratory to the clinic, as well as the most recent information on biodevices and pharmaceutical spinoffs. It highlights presidential and congressional initiatives and programs that may significantly impact the field in the near future. Chapters discuss the latest science and technologies―which are applied to diagnosis and treatment of neurological disorders―as well as regulatory issues that impact product development.

This volume describes advances that have already been translated to the clinic or hold significant promise for future application in nanoneurosurgery, as well as their potential impact. A full-color text, the book contains contributions by more than 120 researchers, original and descriptive illustrations, and more than 3,000 references. Offering broad coverage of nanotechnological applications in diverse areas and addressing FDA regulation and healthcare policy, this volume provides a foundation of ideas and methods for scientists and physicians to devise successful, less invasive procedures for future treatment of nervous system disorders.

Contents

۱. From Nanotechnology to Nanoneuroscience/Nanoneurosurgery and Nanobioelectronics: A Historical Review of Milestones
۲. Nanoneurology and Nanoneurosurgery
۳. Nanopolymers and Nanoconjugates for Central Nervous System Diagnostics and Therapies
۴. Micelles and Liposomes: Lipid Nanovehicles for Intracerebral Drug Delivery
۵. Peptide and Protein-Based Nanoparticles
۶. Endohedral Metallofullerenes, Iron Oxide Agents, and Gold Nanoparticles for Brain Imaging
۷. Carbon Nanoplatforms and Their Application for Neurological Disorders
۸. Dendrimers
۹. Ligand-Based Targeting of Therapeutic and Imaging Agents for Cancer
۱۰. Immune-Based Targeting in Cancer
۱۱. Directed Drug Convection Using Magnetic Nanoparticles as Therapeutic Carriers: Meeting the Challenge of Specific Brain Pharmacotherapeutics, Non-Ligand-Based Central Nervous System Targeting, Including Magnetic Focusing
۱۲. Intralesional and IntraparenchymaI Convection-Enhanced Delivery of Nanoparticles
۱۳. Transport of Nanoparticles across Blood-Brain Barrier
۱۴. Nanomedicine Treatment Strategies That Exploit Unique Characteristics of Tumor Vasculature and Microenvironment
۱۵. Focused Ultrasound for Noninvasive Neuromodulation
۱۶. Nanosensors
۱۷. Implantable Infusion Pumps Incorporating Nanotechnology
۱۸. Nanostructured Surfaces for Intracerebral Neurotransmitter Recording
۱۹. Therapy for Neuronopathic Lysosomal Storage Diseases
۲۰. Nanotechnology for Cerebral Aneurysm Treatment
۲۱. Improving Treatment of Stroke through Nanotechnology
۲۲. Molecular Medical Devices for Nanoneurosurgery
۲۳. Applications of Nanotechnology in Epilepsy
۲۴. Applications of Nanotechnology to Diseases of the Spine
۲۵. Nanoparticle-Based Treatment and Imaging of Brain Tumors: Potentials and Limitations
۲۶. Tumor-Targeted Nanodrugs for Treatment of Primary Brain Tumors
۲۷. Application of Nanotechnology in the Diagnosis and Treatment of Brain Metastasis
۲۸. Nanotechnology in Extra-Axial and Pituitary Tumors
۲۹. Using Nanoparticles in Diagnosis and Treatment of CNS Infection
۳۰. Applications of Nanotechnology in Movement Disorders
۳۱. Nanomedicine in Demyelinating Disease: Application to Diagnosis and Therapy in Multiple Sclerosis
۳۲. Applications of Nanotechnology in Degenerative Disorders of the Brain
۳۳. Brain-Machine Interface and Rehabilitation
۳۴. Nanobioelectronics for Noninvasive Neuronal Therapy
۳۵. In Vitro and In Vivo Techniques to Assess Neurotoxicity of Nanopaiticles
۳۶. Nanorobotics for Neurosurgery
۳۷. Imaging and Tracking Therapeutic Cells with Nanoparticles
۳۸. Micro- and Nanotechnology in Nerve Repair
۳۹. Nanotechnology: Applications to Pediatric Neurosurgery
۴۰. Food and Drug Administration Regulatory Framework for Nanodrugs and Nanodevices and the Combination
۴۱. Nanoneuroscience and Nanoneurosurgery: A Key Component of President Obama’s Brain Mapping Initiative

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