دانلود کتاب نانوپزشکی بالینی: نانوذرات، تصویربرداری، درمان و کاربرد های بالینی
Handbook of Clinical Nanomedicine: Nanoparticles, Imaging, Therapy, and Clinical Applications, 1ed

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This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider’s perspective, and (ii) current applications and their potential in a healthcare setting.

Review

“Dr. Bawa and his team have meticulously gathered the distilled experience of world-class researchers, clinicians and business leaders addressing the most salient issues confronted in product concept development and translation. Knowledge is power, particularly in nanomedicine translation, and this handbook is an essential guide that illustrates and clarifies our way to commercial success.”
―Gregory Lanza, MD, PhD, Professor of Medicine and Oliver M. Langenberg Distinguished Professor, Washington University Medical School, USA

“This is an outstanding, comprehensive volume that crosscuts disciplines and topics fitting individuals from a variety of fields looking to become knowledgeable in medical nanotech research and its translation from the bench to the bedside.”
―Shaker A. Mousa, PhD, MBA, Vice Provost and Professor of Pharmacology, Albany College of Pharmacy and Health Sciences, USA

“Masterful! This handbook will have a welcome place in the hands of students, educators, clinicians and experienced scientists alike. In a rapidly evolving arena, the authors have harnessed the field and its future by highlighting both current and future needs in diagnosis and therapies. Bravo!”
―Howard E. Gendelman, MD, Margaret R. Larson Professor and Chair, University of Nebraska Medical Center, USA

“It is refreshing to see a handbook that does not merely focus on preclinical aspects or exaggerated projections of nanomedicine. Unlike other books, this handbook not only highlights current advances in diagnostics and therapies but also addresses critical issues like terminology, regulatory aspects and personalized medicine.”
―Gert Storm, PhD, Professor of Pharmaceutics, Utrecht University, The Netherlands

About the Author

Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, Virginia that he founded in 2002. He is an inventor, entrepreneur, professor and registered patent agent licensed to practice before the US Patent & Trademark Office. Trained as a biochemist and microbiologist, he has been an active researcher for over two decades. He has extensive expertise in the pharmaceutical sciences, biotechnology, nanomedicine, drug delivery, biodefense, FDA regulatory issues, and patent law. Since 1999, he has held various adjunct faculty positions at Rensselaer Polytechnic Institute in Troy, NY, where he is currently an adjunct professor of biological sciences and where he received his doctoral degree in three years (biophysics/biochemistry). Since 2004, he has been an adjunct professor of natural and applied sciences at NVCC in Annandale, VA. He is a scientific advisor to Teva Pharmaceutical Industries, Ltd., Israel. He has served as a principal investigator of National Cancer Institute SBIRs and reviewer for both the National Institutes of Health and the National Science Foundation. In the 1990s, Dr. Bawa held various positions at the US Patent & Trademark Office, including primary examiner for 6 years. He is a life member of Sigma Xi, co-chair of the Nanotech Committee of the American Bar Association and serves on the Global Advisory Council of the World Future Society. He has authored over 100 publications, co-edited four texts and serves on the editorial boards of numerous peer-reviewed journals, including serving as a special associate editor of Nanomedicine (Elsevier) and an editor-in-chief of the Journal of Interdisciplinary Nanomedicine (Wiley). Some of Dr. Bawa’s awards include the Innovations Prize from the Institution of Mechanical Engineers, London, UK (2008), the Key Award from Rensselaer’s Office of Alumni Relations (2005) and the Lifetime Achievement Award from the American Society for Nanomedicine (2014).

Gerald F. Audette, PhD, has been a faculty member at York University in Toronto, Canada, since 2006. Currently, he is an associate professor in the Department of Chemistry and acting director of the Centre for Research on Biomolecular Interactions at York University. He received his doctorate in 2002 from the Department of Biochemistry at the University of Saskatchewan in Saskatoon, Canada. Working with Drs. Louis T. J. Delbaere and J. Wilson Quail (1995–۲۰۰۱), Dr. Audette’s research focused on the elucidation of the protein–carbohydrate interactions that occur during blood-group recognition (in particular during the recognition of O blood type) using high-resolution X-ray crystallography. Dr. Audette conducted his postdoctoral research at the University of Alberta (2001–۲۰۰۶) in Edmonton, Canada. Working with Drs. Bart Hazes and Laura Frost; his research again utilized high-resolution protein crystallography to examine the correlation between protein structure and biological activity of type IV pilins that are assembled into pili used by bacteria for multiple purposes, including cellular adhesion during infection. It was during these studies that Dr. Audette identified the generation of protein nanotubes from engineered pilin monomers. Dr. Audette also studied the process of bacterial conjugation (or lateral gene transfer) using the F-plasmid conjugative system of Escherichia coli. Current research directions include: structure/function studies of proteins involved in bacterial conjugation systems, the structural and functional characterization of several type IV pilins (the monomeric subunit of the pilus), their assembly systems, and adapting these unique protein systems for applications in bionanotechnology. Dr. Audette has previously served as co-editor- in-chief of the Journal of Bionanoscience (۲۰۰۷–۲۰۱۰), and is currently a subject editor of structural chemistry and crystallography for the journal FACETS.

Israel Rubinstein, MD, is professor of medicine at the College of Medicine, University of Illinois at Chicago, USA. He is member of the section of pulmonary, critical care, allergy and sleep medicine in the Department of Medicine, University of Illinois at Chicago. He is an attending physician at the University of Illinois Hospital and Health Sciences System and Jesse Brown VA Medical Center in Chicago. Dr. Rubinstein is also the associate chief of staff for research and development at the Jesse Brown Veterans Administration Medical Center. Prior to his appointment at the University of Illinois at Chicago, he was associate professor of medicine at the University of Nebraska Medical Center in Omaha, Nebraska, USA. Dr. Rubinstein received his medical degree from the Hebrew University-Hadassah School of Medicine in Jerusalem, Israel. He was a medical resident in Israel, fellow in respirology at the University of Toronto and a research fellow at the Cardiovascular Research Institute, University of California at San Francisco. Dr. Rubinstein holds 18 issued and pending patents and has authored close to 200 peer-reviewed papers in scientific journals. Dr. Rubinstein’s funded research endeavors center around nanomedicine and targeted drug delivery with specific focus on lipid-based products and repurposing. Currently, he serves as editor-in-chief of Nanotechnology, Science and Applications, associate editor of the International Journal of Nanomedicine, and editorial board member of several scientific journals. Dr. Rubinstein is member of the scientific advisory board of the International Academy of Cardiology. He is a fellow of the American Heart Association as well as the American College of Physicians and the American College of Chest Physicians. In addition, he is a member of the American Thoracic Society, American Physiological Society, American Society for Pharmacology and Experimental Therapeutics, and American Microbiology Society. Dr. Rubinstein is a board member and director of Advanced Life Sciences, a publicly traded biopharmaceutical company based in Woodridge, Illinois, USA. He is a co-founder of ResQ Pharma, an emerging clinical stage pharmaceutical company focusing on repurposing FDA-approved drugs for cardiopulmonary resuscitation and drug overdoses.

Contents

Chapter 1: Science at the Nanoscale:Introduction and Historical Perspective
Chapter 2: Nanomedicine: Dynamic Integration of Nanotechnology with Biomedical Science
Chapter 3: A Small Introduction to the World of Nanomedicine
Chapter 4: Top Ten Recent Nanomedical Research Advances
Chapter 5: The Coming Era of Nanomedicine
Chapter 6: What’s in a Name? Defining Nano in the Context of Drug Delivery
Chapter 7: Properties of Nanoparticulate Materials
Chapter 8: Solid Drug Nanoparticles: Methods for Production and Pharmacokinetic Benefits
Chapter 9: Design and Development of Approved Nanopharmaceutical Products
Chapter 10: Nanosizing Approaches in Drug Delivery
Chapter 11: Multilayered Nanopartides for Personalized Medicine: Translation into Clinical Markets
Chapter 12: Nanomaterials for Pharmaceutical Applications
Chapter 13: Polysaccharides as Nanomaterials for Therapeutics
Chapter 14: The Story of C60 Buckminsterfullerene
Chapter 15: Applications of Nanopartides in Medical Imaging
Chapter 16: Nanoimaging for Nanomedicine
Chapter 17: Nanopartides for Multi-Modality Diagnostic Imaging and Drug Delivery
Chapter 18: Magnetic Nanopartides for Magnetic Resonance Imaging: A Translational Push toward Theranostics
Chapter 19: First-in-Human Molecular Targeting and Cancer Imaging Using Ultrasmall Dual-Modality C Dots
Chapter 20: Atomic Force Microscopy for Nanomedicine
Chapter 21: Atomic Force Microscopy Imaging and Probing of Amyloid Nanoaggregates
Chapter 22: Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery
Chapter 23: Viral Nanopartides: Tools for Materials Science and Biomedicine
Chapter 24: Bacterial Secretion Systems: Nanomachines for Infection and Genetic Diversity
Chapter 25: The Vascular Cartographic Scanning Nanodevice
Chapter 26: Advancements in Ophthalmic Glucose Nanosensors for Diabetes Management
Chapter 27: Towards Nanodiagnostics for Bacterial Infections
Chapter 28: Copaxone® in the Era of Biosimilars and Nanosimilars
Chapter 29: Doxil®: The First FDA-Approved Nanodrug From an Idea to a Product (January 2015 Update)
Chapter 30: Nanotechnology and the Skin Barrier: Topical and Transdermal Nanocarrier-Based Delivery
Chapter 31: Application of Nanotechnology in Non-Invasive Topical Gene Therapy
Chapter 32: Nanocarriers in the Therapy of Inflammatory Disease
Chapter 33: Advanced 3D Nano/Microfabrication Techniques for Tissue and Organ Regeneration
Chapter 34: Nanomedidne for Acute Lung Injury/Acute Respiratory Distress Syndrome: A Shifting Paradigm?
Chapter 35: Nanoviricides: Targeted Anti-Viral Nanomaterials
Chapter 36: Nanotechnology in Tissue Engineering for Orthopaedics
Chapter 37: Applications of Nanomaterials in Dentistry
Chapter 38: Biomimetic Applications in Regenerative Medicine: Scaffolds, Transplantation Modules, Tissue Homing Devices, and Stem Cells
Chapter 39: Potential Applications of Nanotechnology in the Nutraceutical Sector
Chapter 40: Designing Nanocarriers for the Effective Treatment of Cardiovascular Diseases
Chapter 41: Carbon Nanotubes as Substrates for Neuronal Growth
Chapter 42: Polymeric Nanopartides for Cancer Therapeutics
Chapter 43: Nanotechnology for Radiation Oncology
Chapter 44: Gold Nanopartides against Cancer
Chapter 45: Solid Lipid Nanopartides and Nanostructured Lipid Carders for Cancer Therapy
Chapter 46: Nanomedicines Targeted to Aberrant Cancer Signaling and Epigenetics
Chapter 47: Biodegradable Nanopartide-Based Antiretroviral Therapy across the Blood-Brain Barrier
Chapter 48: HIV-Specific Immunotherapy with Synthetic Pathogen-Like Nanopartides
Chapter 49: Biomedical Engineering and Nanoneurosurgery: From the Laboratory to the Operating Room
Chapter 50: Nanotechnology-Based Systems for Microbidde Development
Chapter 51: Nanotechnology-Based Solutions to Combat the Emerging Threat of Superbugs: Current Scenario and Future Prospects
Chapter 52: Nanolithography and Biochips’ Role in Viral Detection
Chapter 53: Lectins as Nano-Tools in Drug Delivery
Chapter 54: Diagnostics of Ebola Hemorrhagic Fever Virus
Chapter 55: Nanomedicine as a Strategy to Fight Thrombotic Diseases

قیمت : 7000 تومان
لینک کوتاه : https://bookbaz.ir/?p=33760
نویسنده : Raj Bawa , Gerald F. Audette
ناشر : Pan Stanford
سال انتشار : 2016
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 1686
(ISBN) شابک : 9814669202
قیمت کتاب درآمازون : $560.85
حجم فایل : 28 MB

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۷۰۰۰ تـومان – خرید