دانلود کتاب نانو ذرات در ریه: گرفتن در معرض محیط زیست و دارورسانی
Nanoparticles in the Lung: Environmental Exposure and Drug Delivery, 1ed

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Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells.

Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding of how inhaled nanoparticles behave in the human lungs and body. Featuring contributions from renowned subject-matter experts, this authoritative text describes the sequence of events that nanoparticles encounter in the lungs when moving from the air into the bloodstream. This includes deposition, interactions with the alveolar surface and epithelium, translocation across the air–blood tissue barrier, and accumulation in the body.

In addition, the book addresses practical considerations for drug delivery to the respiratory tract, drug and gene delivery in the lungs, and bio-nanocapsules. It considers the physicochemical, colloidal, and transport properties of nanoparticles, and presents cutting-edge research on special issues such as dosimetry for in vitro nanotoxicology, nanoparticle deposition in the developing lungs, and the potential for nose-to-brain delivery of drugs.

Nanoparticles in the Lung: Environmental Exposure and Drug Delivery offers the most updated and comprehensive knowledge of the risks and benefits associated with nanoparticle inhalation―to protect humans from any harmful effects and to explore the utility of nanoparticles as drug delivery carriers.

Review

“The book presents the state of our current knowledge of the pulmonary-nanoparticle interface in a balanced, extensively researched way… This is a great reference text that I would want on my bookshelf. It also should be on the bookshelves of all students of nanomedicine.”
―Ellis H. Tobin, M.D., Albany Medical College and SUNY College of Nanoscale Science and Engineering, New York, USA

“This book is an incredibly timely and relevant contribution to the scientific community, as nanotechnology advances at breakneck pace. Emerging medical applications as well as the potential for unwanted or adverse health effects due to nanoparticle exposures are both addressed in detail. This work will serve as an excellent resource for researchers, clinicians, public health professionals, and others who are working to advance the state of the science where nanoparticles and the respiratory track collide.”
–Sara Brenner, MD, MPH, SUNY Polytechnic Institute, Colleges of Nanoscale Science and Engineering, Albany, New York, USA

Contents

Chapter 1. Introduction
Chapter 2. Deposition
Chapter 3. Interaction with the Lung Surface
Chapter 4. Role of the Biomolecule Corona in Nanopartide Fate and Behavior
Chapter 5. Interaction with Alveolar Lining Fluid
Chapter 6. Interaction with Lung Macrophages
Chapter 7. Interactions with Alveolar Epithelium
Chapter 8. Mechanistic Aspects of Cellular Uptake
Chapter 9. Cellular Uptake and Intracellular Trafficking
Chapter 10. Translocation across the Air-Blood Tissue Barrier
Chapter 11. The Pulmonary Lymphatic System
Chapter 12. Translocation and Accumulation in the Body
Chapter 13. Practical Considerations for Drug Delivery to the Respiratory Tract
Chapter 14. Drug and Gene Delivery in the Lungs
Chapter 15. Bio-Nanocapsules. Novel Drug Delivery
Chapter 16. Physicochemical, Colloidal, and Transport Properties
Chapter 17. Dosimetry for In Vitro Nanotoxicology. Too Complicated to Consider, Too Important to Ignore
Chapter 18. Potential for Nose-to-Brain Delivery of Drugs
Chapter 19. The Developing Lungs
Chapter 20. Nanotoxicology
Chapter 21. Summary

قیمت : 4000 تومان

لینک کوتاه : https://bookbaz.ir/?p=73130
نویسنده : Akira Tsuda ,‎ Peter Gehr
ناشر : CRC Press; 1 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 388
(ISBN) شابک : 1439892792
قیمت کتاب درآمازون : $179.95
حجم فایل : 40 MB

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