دانلود کتاب پاتولوژی سم شناسی هاشک و روسو: اصول و عملکرد پاتولوژی توکسیکولوژیک (جلد ۱)
Haschek and Rousseaux’s Handbook of Toxicologic Pathology: Principles and Practice of Toxicologic Pathology, Vol-1, 4ed

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Haschek and Rousseaux’s Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters.

Completely revised with a number of new chapters, Volume 1, “Principles and the Practice of Toxicologic Pathology,” covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses “Toxicologic Pathology in Safety Assessment” and “Environmental Toxicologic Pathology”. These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of “Target Organ Toxicity”, emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately.

Review

Updated and expanded, Volume 1 of the Fourth Edition of Handbook of Toxicologic Pathology provides scientists and researchers in industry, academia, and government with coverage of the practice, principles and methods of toxicologic pathology

Contents

Chapter 1. Toxicologic Pathology: An Introduction
Chapter 2. Biochemical and Molecular Basis of Toxicity
Chapter 3. ADME Principles in Small Molecule Drug Discovery and Development: An Industrial Perspective
Chapter 4. Biotherapeutics ADME and PK/PD Principles
Chapter 5. Principles of Pharmacodynamics and Toxicodynamics
Chapter 6. Morphologic Manifestations of Toxic Cell Injury
Chapter 7. The Role of Pathology in Evaluation of Reproductive, Developmental, and Juvenile Toxicity
Chapter 8. Carcinogenesis: Mechanisms and Evaluation
Chapter 9. Basic Approaches in Anatomic Toxicologic Pathology
Chapter 10. Clinical Pathology in Nonclinical Toxicity Testing
Chapter 11. Special Techniques in Toxicologic Pathology
Chapter 12. Digital Pathology and Tissue Image Analysis
Chapter 13. In Vivo Small Animal Imaging: A Comparison to Gross and Histopathologic Observations in Animal Models
Chapter 14. Biomarkers: Discovery, Qualification, and Application
Chapter 15. Toxicogenomics: A Primer for Toxicologic Pathologists
Chapter 16. Experimental Design and Statistical Analysis for Toxicologic Pathologists
Chapter 17. Animal Models in Toxicologic Research: Rodents
Chapter 18. Animal Models in Toxicologic Research: Rabbit
Chapter 19. Animal Models in Toxicologic Research: Dog
Chapter 20. Animal Models in Toxicologic Research: Pig
Chapter 21. Animal Models in Toxicologic Research: Nonhuman Primate
Chapter 22. Animal Models in Toxicologic Research: Nonmammalian
Chapter 23. Genetically Engineered Animal Models in Toxicologic Research
Chapter 24. Alternative Models in Biomedical Research: In Silico, In Vitro, Ex Vivo, and Nontraditional In Vivo Approaches
Chapter 25. Nomenclature and Diagnostic Resources in Anatomic Toxicologic Pathology
Chapter 26. Pathology Peer Review
Chapter 27. Pathology and GLPs, Quality Control, and Quality Assurance
Chapter 28. Practices to Optimize Generation, Interpretation, and Reporting of Pathology Data from Toxicity Studies
Chapter 29. Issues in Laboratory Animal Science That Impact Toxicologic Pathology

قیمت : 10000 تومان
لینک کوتاه : https://bookbaz.ir/?p=252916
نویسنده : Wanda M. Haschek
ناشر : Academic Press; 4th edition
سال انتشار : 2022
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 1082
(ISBN) شابک : 0128210443
قیمت کتاب درآمازون : $250.00
حجم فایل : 110 MB

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