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Electrophysiological Foundations of Cardiac Arrhythmias, 1ed
This book teaches the fundamental concepts of cardiac electrophysiology with an emphasis on the relationship of basic mechanisms to clinical arrhythmias. Understanding this relationship and the underlying mechanisms of arrhythmogenesis will be valuable to medical students in general and physicians entering the fields of cardiology and clinical electrophysiology, as well as those scientists and clinicians already working in this field.
The foundations of electrophysiology are explained in a way that will enable the student/reader to go on to more advanced texts such as Josephson s Clinical Cardiac Electrophysiology by Mark E. Josephson (Wolters Kluwer), who is one of the authors of this book. It is not a complete review of basic cellular electrophysiology and only focuses on aspects that are relevant to the arrhythmogenic mechanisms. Similarly, it is not a complete compendium on electrophysiology of clinical arrhythmias. Only selected arrhythmias are described that best illustrate the translation of the basic electrophysiological mechanism to the clinic.
The book is divided into three parts that cover the major mechanisms of arrhythmogenesis: Part I Automaticity, Part II Afterdepolarizations and Triggered Activity, and Part III Abnormal Impulse Conduction and Reentry. Each part starts with a chapter that describes the basic science principles related to that particular mechanism. Topics include: impulse initiation and rate control, membrane currents, conduction, and the effects of programmed electrical stimulation and pharmacologic agents. Subsequent chapters in each part are organized around examples of clinical arrhythmias and then focus on the relevant EP mechanisms and the characteristic responses to interventions. The characteristics of the three different mechanisms are compared and contrasted throughout the text.
Each example works through these three key questions:
۱. What are the ECG characteristics of the arrhythmia?
۲. What is the underlying electrophysiological mechanism?
۳. What are the characteristic properties of the arrhythmia that point to its mechanism?
Throughout the book, the aspects of basic EP mechanisms and examples from EP studies and pharmacologic interventions are paired with clinical examples. The end result is enhanced understanding of how EP mechanisms and testing relate to arrhythmogenesis in a way that can be applied broadly to a variety of situations in a clinical setting.
This definitive book also includes:
More than 300 figures, including ECGs and original diagrams that illustrate essential electrophysiology concepts.
Case studies of clinical arrhythmias with explanations of how ECG characteristics and the responses to electrical stimulation denote arrhythmogenic mechanisms.
Electrophysiological Foundations of Cardiac Arrhythmias by Wit, Josephson, and Wellens is a long overdue text bridging basic science and clinical medicine, thus providing basic scientists, clinical investigators and practicing physicians, unique insights into the mechanisms underlying cardiac arrhythmias. The complex mechanisms responsible for the development of clinical arrhythmias are discussed in detail, but with clarity and appreciation of continuing gaps in our knowledge.
–Charles Antzelevitch, PhD, FACC, FAHA, FHRS; Lankenau Institute for Medical Research; Philadelphia, Pennsylvania
I read Electrophysiological Foundations of Cardiac Arrhythmias, written by three icons of cardiac electrophysiology with great joy. This is an amazingly comprehensive text, written so that students of all ability level can understand the basic mechanisms of cardiac electrophysiology. My friend Mark Josephson often complained that contemporary electrophysiology had become electrotechnology. Physicians had become so concerned with doing things (implanting ICDs, performing ablations) that the underlying understanding of what they were doing was often missed. This text provides a powerful antidote to electrotechnology, appropriate for all true students of electrophysiology. –David J. Callans, MD; University of Pennsylvania Health System Philadelphia, Pennsylvania
It is fair to say that this textbook is a gem, and one every electrophysiologist should want to have. It is one of the last masterpieces that Mark Josephson contributed to with his friends and life-long colleagues, Hein J. Wellens and Andrew L. Wit. It reflects their unique perspective on the integration of basic science into an understanding of human clinical electrophysiology. We are talking about bench to bedside, and this fine volume includes some of the best basic and clinical science I have read anywhere. The book is an essential addition to every electrophysiologist s library. –Kenneth A. Ellenbogen, MD; VCU School of Medicine Richmond, Virginia
CHAPTER 1: Basic Principles of Normal Automaticity
CHAPTER 2: Sinus Node Normal Automaticity and Automatic Arrhythmias
CHAPTER 3: Atrial, A-V Junctional, and Ventricular Normal Automaticity, and Automatic Arrhythmias
CHAPTER 4: Abnormal Automaticity: Basic Principles and Arrhythmias
CHAPTER 5: Basic Principles of Delayed Afterdepolarizations and Triggered Action Potentials
CHAPTER 6: Delayed Afterdepolarizations: Triggered Arrhythmias
CHAPTER 7: Basic Principles of Early Afterdepolarizations and Triggered
CHAPTER 8: Early Afterdepolarizations: Triggered Arrhythmias
CHAPTER 9: Basic Principles of Reentry: Altered Conduction
CHAPTER 10: Atrial Reentrant Arrhythmias
CHAPTER 11: Atrioventricular (A-V) Junctional Reentrant Arrhythmias
CHAPTER 12: Ventricular Reentrant Arrhythmias
لینک کوتاه : https://bookbaz.ir/?p=67569
نویسنده : Andrew L. Wit , Hein J. Wellens
ناشر : Cardiotext Publishing; 1 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF (نسخه تبدیلی)
تعداد صفحات : 689
(ISBN) شابک : 0979016452
قیمت کتاب درآمازون : $221.11
حجم فایل : 18 MB