دنلود کتاب پاتولوژی تشخیصی مولکولی
Diagnostic Molecular Pathology, 1ed

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Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described.

The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests.

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions.

  • Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient
  • Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease
  • Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions
  • Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Review

Diagnostic Molecular Pathology is destined to become an important cornerstone and go-to volume for pathologists, researchers, and clinicians―indeed anyone who wants to understand the approach and application of modern molecular techniques in disease detection and diagnosis. Drs. Coleman and Tsongalis―and their impressive stable of contributors―are to be congratulated for making the exciting and rapidly expanding science of molecular diagnosis accessible to the novice, while also providing the expert with important details on the nuances.  Beyond just a compendium of useful information, it is a well-curated journey through basic concepts, infectious diseases, malignancy, hematopathology, and genetic diseases―and even includes access to a website with lab test videos and decision-making exercises.” –Richard N. Mitchell, MD, PhD (Brigham and Women’s Hospital and Harvard Medical School)

“With much fanfare, molecular techniques have revolutionized clinical medicine, from diagnosis to personalized medical therapeutics.  It is with this background that Diagnostic Molecular Pathology approaches the daunting task of summarizing the advances in the field from infectious disease, heritable and acquired genetic diseases, hematological malignancies, to pharmacogenomics.  In a comprehensive publication, the editors perform a yeoman’s effort in covering this dynamic and exciting field.” –Lawrence M. Silverman, PhD (University of Virginia School of Medicine)

“Diagnostic Molecular Pathology provides a panoramic view of diagnostic molecular pathology testing, written by leaders in the field.  It is a great reference and learning tool.” –Dani S. Zander, MD (University of Cincinnati Medical Center)

Contents

Chapter 1. Basic Concepts in Molecular Pathology—Introduction to Molecular Testing in Human Disease
Chapter 2. Laboratory Approaches in Molecular Pathology—The Polymerase Chain Reaction
Chapter 3. Next-Generation Sequencing in the Clinical Laboratory
Chapter 4. Automation of the Molecular Diagnostic Laboratory
Chapter 5. Molecular Testing for Human Imunodeficiency Virus
Chapter 6. Molecular Testing in Hepatitis Virus Related Disease
Chapter 7. Molecular Testing for Human Papillomaviruses
Chapter 8. Molecular Testing for Herpes Viruses
Chapter 9. Molecular Testing for Parvoviruses
Chapter 10. Molecular Testing for Polyomaviruses
Chapter 11. Molecular Testing for Respiratory Viruses
Chapter 12. Molecular Testing for Diseases Associated with Bacterial Infections
Chapter 13. Agents Associated with Sexually Transmitted Infections
Chapter 14. Molecular Methods for Healthcare-Acquired Infections
Chapter 15. Molecular Testing in Emerging Infectious Diseases
Chapter 16. Noninvasive Prenatal Screening (NIPS) for Fetal Aneuploidies
Chapter 17. Molecular Testing in Inherited Cardiomyopathies
Chapter 18. Molecular Diagnostics for Coagulopathies
Chapter 19. Molecular Diagnosis of Cystic Fibrosis
Chapter 20. Molecular Testing in Hemochromatosis
Chapter 21. Molecular Testing in Breast Cancer
Chapter 22. Molecular Pathology of Prostate Cancer
Chapter 23. Molecular Testing in Lung Cancer
Chapter 24. Molecular Testing in Colorectal Cancer
Chapter 25. Molecular Pathology and Testing in Melanocytic Tumors
Chapter 26. Molecular Testing for Glioblastoma
Chapter 27. Molecular Testing in Pancreatic Cancer
Chapter 28. Molecular Testing in Gynecologic Cancer
Chapter 29. The Emerging Genetic Landscape in Renal Cell Carcinoma
Chapter 30. Molecular Testing in Thyroid Cancer
Chapter 31. Molecular Testing in Pediatric Cancers
Chapter 32. Molecular Testing in Chronic Myelogenous Leukemia
Chapter 33. Molecular Testing in Acute Myeloid Leukemia
Chapter 34. Molecular Testing in Myeloproliferative Neoplasms
Chapter 35. Molecular Testing in the Assessment of Bone Marrow Transplant Engraftment
Chapter 36. Personalized Medicine in Cardiovascular Disease
Chapter 37. Personalized Medicine for Coagulopathies
Chapter 38. Personalized Medicine for Hepatitis C Virus
Chapter 39. Personalized Medicine in Cancer Treatment
Chapter 40. Imaging Mass Spectrometry in Clinical Pathology
Chapter 41. Whole Genome Sequencing in the Molecular Pathology Laboratory

قیمت : 5000 تومان
لینک کوتاه : https://bookbaz.ir/?p=101116
نویسنده : William B. Coleman , Gregory J. Tsongalis
ناشر : Academic Press; 1 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 532
(ISBN) شابک : 9780128008867
قیمت کتاب درآمازون : $118.03
حجم فایل : 15 MB

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۵۰۰۰ تـومان – خرید