دانلود کتاب اصول و تمرین ایمونوتراپی سرطان
Cancer Immunotherapy Principles and Practice, 1ed

“Drs. Butterfield, Kaufman and Marincola on behalf of the SITC have created a comprehensive must-have resource covering the basic and translational science behind approved and investigational immune therapies, and disease-by-disease clinical application of the therapies, written by leaders in the field. The textbook will be highly valuable reading for those just entering the field and for experienced scientists and clinicians looking to expand their knowledge base.” ―Mario Sznol, MD, Professor of Medicine (Medical Oncology), Yale School of Medicine, New Haven, Connecticut

Cancer Immunotherapy Principles and Practice, from the Society for Immunotherapy of Cancer (SITC), is the authoritative reference on cancer immunobiology and the immunotherapy treatments that harness the immune system to combat malignant disease.

Featuring five sections and over 50 chapters covering the Basic Principles of Tumor Immunology, Cancer Immunotherapy Targets and Classes, Immune Function in Cancer Patients, Disease-Specific Treatments and Outcomes, and Regulatory Aspects of Cancer Immunotherapy, this book covers all major topics that have shaped the development of immunotherapy and propelled it to its current place at the forefront of cancer treatment innovation.

This volume is a comprehensive resource for oncologists and fellows, immunologists, cancer researchers, and related practitioners seeking understanding of the basic science and clinical applications of cancer immunotherapy. As well as presenting the evidence for immune-based cancer treatment, it positions immunotherapy in the context of other available cancer treatments and provides data on response rates, risks, and toxicities across a variety of diseases. Filled with detailed tables, and instructive illustrations, as well as key points for quick reference, Cancer Immunotherapy Principles and Practice simplifies a challenging and dynamic subject.

KEY FEATURES

  • Clearly summarizes the basic principles and research supporting cancer immunotherapy clinical translation
  • Contains expert guidance and treatment strategies for all immunotherapy classes and agents, including cell-based therapies, monoclonal antibodies, cytokine therapies, checkpoint inhibitors, oncolytic viruses, adjuvant approaches, and treatment combinations
  • Includes expert perspectives from leading authorities in the field
  • Provides information on all FDA-approved immunotherapies, including clinical management and outcome data
  • Discusses clinical aspects of immunotherapy for individual cancer types, including melanoma and other skin cancers, lung cancers, gynecologic cancers, gastrointestinal cancers, hematologic cancers, genitourinary cancers, head and neck cancers, sarcomas, brain and other CNS cancers, breast cancer, and pediatric malignancies.
  • Explains regulatory aspects behind the development and approval of immunotherapy drugs
  • Includes Online Access to the Digital Book

Contents

Chapter 1: History of Cancer Immunotherapy
Chapter 2: Introduction to Basic Sciences— Cracking the Code of Cancer Immune Responsiveness and the Evolution of Cancer Biology
Chapter 3: Human Tumor Antigens Recognized by T Lymphocytes
Chapter 4: HLA ClassIAntigen-Processing Machinery in Cancer
Chapter 5: Systems Biology of T Cells
Chapter 6: Activation of CD4+ T Lymphocytes
Chapter 7: Regulation of Cell-Mediated Immunity: The Biology of Checkpoints and Regulatory T Cells
Chapter 8: The Role of Breg Cells in Modulating the Antitumor Immune Response
Chapter 9: The Innate Immune System: Natural Killer Cells
Chapter 10: The Innate Immune System: Macrophages
Chapter 11: Natural Killer Cell Effector Mechanisms Against Solid Tumors and Leukemias and Their Exploitation in Immunotherapy
Chapter 12: Role of the Microbiota in Homeostasisr Carcinogenesisr and Therapy
Chapter 13: Chemokines and Chemokine Receptors: Regulators of the Balance Between Antitumor and Protumor Immunity and Promising Targets in Cancer Immunotherapy
Chapter 14: Role of the Tumor Microenvironment
Chapter 15: Introduction to Principles of Cancer Immunotherapy
Chapter 16: Manipulating Innate Immune Path’ways as Cancer Immunotherapy
Chapter 17: Cancer Vaccines: Considerations of Antigenr Formulationr and Delivery
Chapter 18: T Cell Modulatory Cytokines
Chapter 19: Adoptive T Cell Transfer
Chapter 20: Immunotherapy Based on Blocking T Cell Inhibitory Pathways
Chapter 21: Agonistic Antibodies to Co-Stimulatory Molecules
Chapter 22: Immune Effects of Conventional Cancer Therapeutics
Chapter 23: Oncolytic Viruses
Chapter 24: Principles of Combination Immunotherapies
Chapter 25: Introduction to Immune Function in Cancer Patients
Chapter 26: Tumor-Infiltrating Immune Cells of Myeloid Origin
Chapter 27: Intratumoral Gene Signatures and Host Genetic Variations Associated With Immune Responsiveness
Chapter 28: Impact of Somatic Mutations on the Local and Systemic Antitumor Immune Response
Chapter 29: Tumor Antigen Profiling
Chapter 30: Assessment of Antitumor Immunity in Blood and Lymph Nodes
Chapter 31: Regulatory T Cell Biology and Its Application in Cancer
Chapter 32: Systemic Measures of Immune Function in Cancer Patients: Other Suppressive Cellular Mechanisms
Chapter 33: Circulating Mediators of Tumor-Induced Immune Suppression
Chapter 34: The Multifaceted Roles of B Cells and Plasma Cells in Antitumor Immunity
Chapter 35: Systems Immunology Approaches to Cancer Immunotherapy
Chapter 36: Tumor Microenvironment Metabolism as a Primordial Checkpoint in Antitumor T Cell Immunity
Chapter 37: Age-Related Immune Function Changes as They Relate to Cancer Immunotherapy
Chapter 38: Clinical Measures: Imagingr Pseudoprogression, and Metabolism
Chapter 39: Introduction: General Approach to Cancer Immunotherapy— Lessons Learned From the Past Years
Chapter 40: Immunotherapy in Melanoma
Chapter 41: Other Cutaneous Tumors: Basal Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, and Merkel Cell Carcinoma
Chapter 42: Immunotherapy in Genitourinary Malignancies
Chapter 43: Immunotherapy in Gastrointestinal Cancers
Chapter 44: Immunotherapy of Hepatocellular Carcinoma
Chapter 45: Immunotherapy for Gynecologic Malignancies
Chapter 46: Breast Cancer Immunotherapy
Chapter 47: Lung Cancer
Chapter 48: Head and Neck Cancer
Chapter 49: Immunotherapy of Hematologic Malignancies: Lymphomas, Leukemias, and Myeloma
Chapter 50: Brain Tumors
Chapter 51: Sarcomas
Chapter 52: Pediatric Cancers: Neuroblastoma
Chapter 53: A Regulatory Perspective on Cell Therapy for Cancer: Chemistry, Manufacturing and Control, and Preclinical and Clinical Considerations
Chapter 54: Gene Therapy-Based Immunotherapy Products for Human Clinical Trials: Chemistry, Manufacturing and Control, Preclinical and Clinical Considerations— An FDA Perspective
Chapter 55: Regulatory Considerations for In Vitro Diagnostic Devices

قیمت : 6000 تومان

لینک کوتاه : https://bookbaz.ir/?p=65176
نویسنده : Lisa H. Butterfield PhD , Howard L. Kaufman MD FACS
ناشر : Demos Medical; 1 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 921
(ISBN) شابک : 1620700972
قیمت کتاب درآمازون : $265.00
حجم فایل : 15 MB

51ee66up6RL._SX358_BO1,204,203,200_

۶۰۰۰ تـومان – خرید