دانلود کتاب اقلام دارویی محاسباتی: برنامه مدلسازی مولکولی در تحویل دارو
Computational Pharmaceutics: Application of Molecular Modeling in Drug Delivery, 1ed

Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques  are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems.  The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems.  Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field.  This book is included in the Advances in Pharmaceutical Technology book series.

Contents

Chapter 1 Introduction to Computational Pharmaceutics
Chapter 2 Crystal Energy Landscapes for Aiding Crystal Form Selection
Chapter 3 Solubilization of Poorly Soluble Drugs: Cyclodextrin-Based Formulations
Chapter 4 Molecular Modeling of Block Copolymer Self-Assembly and Micellar Drug Delivery
Chapter 5 Solid Dispersion-a Pragmatic Method to Improve the Bioavailability of Poorly Soluble Drugs
Chapter 6 Computer Simulations of Lipid Membranes and Liposomes for Drug Delivery
Chapter 7 Molecular Modeling for Protein Aggregation and Formulation
Chapter 8 Computational Simulation of Inorganic Nanoparticle Drug Delivery Systems at the Molecular Level
Chapter 9 Molecular and Analytical Modeling of Nanodiamond for Drug Delivery Applications
Chapter 10 Molecular Modeling of Layered Double Hydroxide Nanopartides for Drug Delivery
Chapter 11 Molecular Modeling as a Tool to Understand the Role of Poly(Ethylene) Glycol in Drug Delivery
Chapter 12 3D Structural Investigation of Solid Dosage Forms
Chapter 13 Physiologically Based Pharmacokinetic Modelling in Drug Delivery

قیمت : 5000 تومان

لینک کوتاه : https://bookbaz.ir/?p=16138
نویسنده : Defang Ouyang , Sean C. Smith
ناشر : Wiley; 1 edition
سال انتشار : 2015
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 340
(ISBN) شابک : 1118573994
قیمت کتاب درآمازون : $106.30
حجم فایل : 5 MB

51fjXpliGsL._SX346_BO1,204,203,200_

۵۰۰۰ تـومان – خرید