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Green Biocatalysis, 1ed

Green Biocatalysis presents an exciting green technology that uses mild and safe processes with high regioselectivity and enantioselectivity. Bioprocesses are carried out under ambient temperature and atmospheric pressure in aqueous conditions that do not require any protection and deprotection steps to shorten the synthetic process, offering waste prevention and using renewable resources.

Drawing on the knowledge of over 70 internationally renowned experts in the field of biotechnology, Green Biocatalysis discusses a variety of case studies with emphases on process R&D and scale-up of enzymatic processes to catalyze different types of reactions. Random and directed evolution under process conditions to generate novel highly stable and active enzymes is described at length. This book features:

A comprehensive review of green bioprocesses and application of enzymes in preparation of key compounds for pharmaceutical, fine chemical, agrochemical, cosmetic, flavor, and fragrance industries using diverse enzymatic reactions
Discussion of the development of efficient and stable novel biocatalysts under process conditions by random and directed evolution and their applications for the development of environmentally friendly, efficient, economical, and sustainable green processes to get desired products in high yields and enantiopurity
The most recent technological advances in enzymatic and microbial transformations and cuttingedge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts

With over 3000 references and 800 figures, tables, equations, and drawings, Green Biocatalysis is an excellent resource for biochemists, organic chemists, medicinal chemists, chemical engineers, microbiologists, pharmaceutical chemists, and undergraduate and graduate students in the aforementioned disciplines.

About the Author

Ramesh N. Patel, Ph.D., has 44 years of experience in pharmaceutical and chemical industries. He obtained his Ph.D. in Biochemistry from the University of Texas, Austin, and completed an NIH and ACS Postdoctoral Research Fellowship in Biology from Yale University, New Haven. His professional experience includes working in Bristol-Myers Squibb and ExxonMobil Research and Engineering, where he has a record of achievements including over 175 original publications, 79 process patents, and over 113 invited/external presentations. Dr. Patel is the recipient of the 2004 Biotechnology Lifetime Achievement Award from the American Oil Chemists’ Society, the 2008 Biocat Industrial Research Award from the International Congress on Biocatalysis, and the 2012 Distinction of Academic Award from the International Society of World Academy of Biocatalysis and Agricultural Biotechnology. Currently he is working as a consultant in Biocatalysis and Biotechnology.

Chapter 1 Biocatalysis and Green Chemistry
Chapter 2 Enzymatic Synthesis of Chiral Amines using ©-Transaminases, Amine Oxidases, and the Berberine Bridge Enzyme
Chapter 3 Decarboxylation and Racemization of Unnatural Compounds using Artificial Enzymes Derived from Arylmalonate Decarboxylase
Chapter 4 Green Processes for the Synthesis of Chiral Intermediates for the Development of Drugs
Chapter 5 Dynamic Kinetic Resolution of Alcohols, Aminesr and Amino Acids
Chapter 6 Recent Developments in Flavin-Based Catalysis: Enzymatic Sulfoxidation
Chapter 7 Development of Chemoenzymatic Processes: An Industrial Perspective
Chapter 8 Epoxide Hydrolases and their Application in Organic Synthesis
Chapter 9 Enantioselective Acylation of Alcohol and Amine Reactions in Organic Synthesis
Chapter 10 Recent Advances in Enzyme-Catalyzed Aldol Addition Reactions
Chapter 11 Enzymatic Asymmetric Reduction of Carbonyl Compounds
Chapter 12 Nitrile-Converting Enzymes and their Synthetic Applications
Chapter 13 Biocatalytic Epoxidation for Green Synthesis
Chapter 14 Dynamic Kinetic Resolution via Hydrolase-Metal Combo Catalysis
Chapter 15 Discovery and Engineering of Enzymes for Peptide Synthesis and Activation
Chapter 16 Biocatalysis for Drug Discovery and Development
Chapter 17 Application of Aromatic Hydrocarbon Dioxygenases
Chapter 18 Ene-reductases and their Applications
Chapter 19 Recent Developments in Aminopeptidasesr Racemases, and Oxidases
Chapter 20 Biocatalytic Cascades for API Synthesis
Chapter 21 Yeast-Mediated Stereoselective Synthesis
Chapter 22 Biocatalytic Introduction of Chiral Hydroxy Groups using Oxygenases and Hydratases
Chapter 23 Asymmetric Synthesis with Recombinant Whole-Cell Catalysts
Chapter 24 Lipases and Esterases as User-Friendly Biocatalysts in Natural Product Synthesis
Chapter 25 Hydroxynitrile Lyases for Biocatalytic Synthesis of Chiral Cyanohydrins
Chapter 26 Biocatalysis: Nitrilases in Organic Synthesis
Chapter 27 Biotechnology for the Production of Chemicals, Intermediates, and Pharmaceutical Ingredients
Chapter 28 Microbial Transformations of Pentacyclic Triterpenes
Chapter 29 Transaminases and their Applications

قیمت : 3000 تومان

لینک کوتاه : https://bookbaz.ir/?p=52122
نویسنده : Ramesh N. Patel
ناشر : Wiley; 1 edition
سال انتشار : 2016
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 795
(ISBN) شابک : 1118822293
قیمت کتاب درآمازون : $225.00
حجم فایل : 15 MB

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Green Biocatalysis, 1ed