دانلود کتاب متاستازهای مغز از تومورهای اولیه (۳ جلدی)
Brain Metastases from Primary Tumors, 3-Vol, 1ed

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection.

  • The only comprehensive reference detailing the link between primary cancers and brain metastases
  • Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer
  • Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain
  • Documents temporal and gender-related trends in brain metastases from other cancers
  • Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors fills that gap, serving as the first two-part reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age- and gender-related trends are also discussed, as is the use of biomarkers for early detection.

  • The only comprehensive reference detailing the link between primary cancers and brain metastases
  • Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer
  • Provides education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain
  • Documents temporal and gender-related trends in brain metastases from other cancers
  • Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available
  • The only comprehensive reference detailing the link between primary cancers and brain metastases

Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood.

Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book.

The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers.

  • Presents the only comprehensive reference detailing the link between primary cancers and brain metastases in melanoma
  • Aids the target audience in discussing various treatment options for patients with brain metastases from melanoma
  • Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

About the Author

Dr. Hayat has published extensively in the fields of microscopy, cytology, immunohistochemistry, immunocytochemistry, and antigen retrieval methods. He is Distinguished Professor, Department of Biological Sciences, Kean University, Union, New Jersey, USA.

قیمت : 8000 تومان

لینک کوتاه : https://bookbaz.ir/?p=80188
نویسنده : M. A. Hayat
ناشر : Academic Press; 1 edition
سال انتشار : 2016
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 802
(ISBN) شابک : 0128035080
قیمت کتاب درآمازون : $200.00
حجم فایل : 28 MB

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