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Signaling Pathways in Liver Diseases, 3ed

Signaling Pathways in Liver Diseases, Third Edition again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format.

With increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as:

  • Autophagy
  • Notch Pathway
  • P13K/PTEN Signaling in Liver Diseases
  • Sirtuins
  • Hepcidin and Iron
  • Epigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis
  • Oxidative Stress and Signaling in the Liver.

Professors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge.

Signaling Pathways in Liver Disease, Third Edition is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.

About the Author

Professor Jean-François Dufour, MD, PhD, Chief, Department of Clinical Pharmacology, University Clinic Visceral Surgery and Medicine, Bern, Switzerland.
Professor Dufour is on the governing board of the European Association for the Study of the Liver (EASL).  He also serves as Associate Editor for the Wiley journal Liver International and is on the editorial board for the following journals: Journal of Hepatology; Clinical Science; World Journal of Gastroenterology

Professor Pierre-Alain Clavien, MD, PhD, FACS, FRCS (Eng), FRCS (Ed), Professor and Chairman, Department of Surgery. Head, Division of Visceral & Transplantation Surgery, University Hospital Zurich, Switzerland.
Professor Clavien is a world-wide renowned surgeon-scientist, currently professor and chairman of the Department of Surgery in Zurich, Switzerland.  His areas of research include organ preservation, liver ischemia-reperfusion injury and regeneration, and pathogenesis of cancer, as well as outcome research. He received many competitive grants and awards, including one of the most prestigious prices for scientific research, the Otto Naegeli Award.

Contents

Chapter 1 Hepatocytes
Chapter 2 Signaling pathways in biliary epithelial cells
Chapter 3 Stellate cells
Chapter 4 Kupffer cells
Chapter 5 Hepatic sinusoidal endothelial cells
Chapter 6 Extracellular matrix
Chapter 7 Platelets: a new cell type in liver physiology
Chapter 8 Immune cell communication in liver disease and liver regeneration
Chapter 9 Extracellular vesicle RNA in liver disease
Chapter 10 Endoplasmic reticulum stress in nonalcoholic fatty liver disease
Chapter 11 Autophagy
Chapter 12 CXC chemokine receptor signaling in liver repair and regeneration
Chapter 13 Metabolic regulation of liver regeneration
Chapter 14 TNF signaling
Chapter 15 Fas/FasL
Chapter 16 Interferon signaling
Chapter 17 Endocannabinoid signaling in liver pathologies
Chapter 18 The WNT/p-eatenin pathway
Chapter 19 Hedgehog signaling in the liver
Chapter 20 Notch pathway
Chapter 21 PI3K/PTEN signaling in liver diseases
Chapter 22 mTOR signaling in liver disease
Chapter 23 LKB1/AMPK path’way in the control of hepatic energy metabolism
Chapter 24 NF-KB
Chapter 25 c-Jun NH2-terminal kinases in liver diseases
Chapter 26 p53
Chapter 27 Sirtuins
Chapter 28 Bile acids and their receptors
Chapter 29 Hepcidin and iron
Chapter 30 Gut microbiome and Iyer diseases
Chapter 31 Epigenetic regulation of hepatic stellate cells and liver fibrosis
Chapter 32 Signaling in hepatocellular carcinoma
Chapter 33 Interplay between hepatitis B virus and innate immune signaling path’ways
Chapter 34 Signaling of hepatitis C virus
Chapter 35 Oxidative stress and signaling in the liver

قیمت : 5000 تومان

لینک کوتاه : https://bookbaz.ir/?p=52636
نویسنده : Jean-Francois Dufour , Pierre-Alain Clavien
ناشر : Wiley-Blackwell; 3 edition
سال انتشار : 2015
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 520
(ISBN) شابک : 111866339X
قیمت کتاب درآمازون : $255.00
حجم فایل : $255.00

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