دانلود کتاب پلاسمیدها: زیست شناسی و تاثیر در بیوتکنولوژی و اکتشاف
Plasmids: Biology and Impact in Biotechnology and Discovery, 1ed

Explore the remarkable discoveries in the rapidly expanding field of plasmid biology

Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of “omics” disciplines, has recently ignited a new wave of interest in plasmids.

This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade.

Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.

Review

“The study and utilization of plasmids is experiencing renewed interest. This book is a comprehensive and illustrative source where readers can find the latest advances in all aspects of plasmids, from the basic understanding of their biology to their utilization as tools in the modern laboratory.” Luis A. Actis, Professor and Chair, Department of Microbiology, Miami University “Plasmids: Biology and Impact in Biotechnology and Discovery compiles information on the recent progress achieved in the field of Plasmid Biology. It constitutes a wealth of inextinguishable knowledge, and is an important reference for all scientists working in the expanding and interconnected world of modern biology.” Prof. Manuel Espinosa, Professor ‘ad honorem’ at the Centro de Investigaciones Biológicas from the Consejo Superior de Investigaciones Científicas

About the Author

Marcelo E. Tolmasky is a Professor at the Department of Biology, California State University, Fullerton, and the Director of the Center for Applied Biotechnology Studies. He did his PhD at the Fundación Instituto Leloir under the mentorship of Luis F. Leloir and his postdoctoral training in Jorge H. Crosa’s laboratory at the Oregon Health & Sciences University, where he studied virulence and antibiotic resistance plasmids in Gram-negatives. His current research focuses on several basic and applied aspects of plasmid-mediated multidrug resistance and virulence. He was a coeditor of the book Enzyme-Mediated Resistance to Antibiotics: Mechanisms, Dissemination, and Prospects for Inhibition (ASM Press).

Juan C. Alonso is a Research Professor at the Centro Nacional de Biotecnología (CSIC), Madrid, Spain. He did his PhDs at the School of Veterinary Science and Exact and Natural Sciences under the mentorship of Eduardo Zaccardi and Oscar Grau, respectively. He completed his postdoctoral training studying plasmid and chromosomal horizontal gene transfer in Bacillus subtilis in Thomas Trautner’s lab at the Max-Planck-Institute for Molecular Genetics, Berlin, Germany. Current research in his laboratory focuses on genomic stability in Firmicutes. Through genetic, cytological, biochemical, and biophysics approaches, the long-term goal is to define the molecular steps in the dynamic process of homologous recombination and DNA segregation.

Chapter 1 : Historical Events That Spawned the Field of Plasmid Biology
Chapter 2 : Iteron Plasmids
Chapter 3 : Mechanisms of Theta Plasmid Replication
Chapter 4 : Plasmid Rolling-Circle Replication
Chapter 5 : Replication and Maintenance of Linear Phage-Plasmid N15
Chapter 6 : Plasmid Replication Control by Antisense RNAs
Chapter 7 : Topological Behavior of Plasmid DNA
Chapter 8 : Plasmid Partition Mechanisms
Chapter 9 : Resolution of Multimeric Forms of Circular Plasmids and Chromosomes
Chapter 10 : Conditional Activation of Toxin-Antitoxin Systems: Postsegregational Killing and Beyond
Chapter 11 : The Interplay between Different Stability Systems Contributes to Faithful Segregation: Streptococcus pyogenes pSM19035 as a Model
Chapter 12 : The CRISPR-Cas Immune System and Genetic Transfers: Reaching an Equilibrium
Chapter 13 : Plasmid Diversity and Adaptation Analyzed by Massive Sequencing of Escherichia coli Plasmids
Chapter 14 : Conjugation in Gram-Positive Bacteria
Chapter 15 : Mobilizable Rolling-Circle Replicating Plasmids from Gram-Positive Bacteria: A Low-Cost Conjugative Transfer
Chapter 16 : The Plasmid Mobilome of the Model Plant-Symbiont Sinorhizobium meliloti: Coming up with New Questions and Answers
Chapter 17 : The Agrobacterium Ti Plasmids
Chapter 18 : The Influence of Biofilms in the Biology of Plasmids
Chapter 19 : The Partitioning and Copy Number Control Systems of the Selfish Yeast Plasmid: An Optimized Molecular Design for Stable Persistence in Host Cells
Chapter 20 : Plasmids from Euryarchaeota
Chapter 21 : The Plasmidome of Firmicutes: Impact on the Emergence and the Spread of Resistance to Antimicrobials
Chapter 22 : Plasmid-Mediated Antimicrobial Resistance in Staphylococci and Other Firmicutes
Chapter 23 : Plasmid Detection, Characterization, and Ecology
Chapter 24 : Plasmid-Mediated Antibiotic Resistance and Virulence in Gram-Negatives: The Klebsiella pneumoniae Paradigm
Chapter 25 : Plasmid-Mediated Quinolone Resistance
Chapter 26 : Plasmid-Mediated Tolerance Toward Environmental Pollutants
Chapter 27 : Virulence Plasmids of Spore-Forming Bacteria
Chapter 28 : Virulence Plasmids of Nonsporulating Gram-Positive Pathogens
Chapter 29 : Plasmid-Encoded Iron Uptake Systems
Chapter 30 : DNA Assembly Tools and Strategies for the Generation of Plasmids
Chapter 31 : Plasmids as Tools for Containment
Chapter 32 : Mining Environmental Plasmids for Synthetic Biology Parts and Devices
Chapter 33 : Using Plasmids as DNA Vaccines for Infectious Diseases
Chapter 34 : Plasmid Biopharmaceuticals

قیمت : 5000 تومان

لینک کوتاه : https://bookbaz.ir/?p=25630
نویسنده : Marcelo E. Tolmasky , Juan Carlos Alonso
ناشر : ASM Press; 1 edition
سال انتشار : 2015
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 720
(ISBN) شابک : 1555818978
قیمت کتاب درآمازون : $142.50
حجم فایل : 35 MB

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دانلود کتاب پلاسمیدها: زیست شناسی و تاثیر در بیوتکنولوژی و اکتشافPlasmids: Biology and Impact in Biotechnology and Discovery, 1ed

Review

About the Author

Contents

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دانلود کتاب پلاسمیدها: زیست شناسی و تاثیر در بیوتکنولوژی و اکتشاف
Plasmids: Biology and Impact in Biotechnology and Discovery, 1ed