دانلود کتاب کیفیت در هموستاز و ترومبوز آزمایشگاهی
Quality in Laboratory Hemostasis and Thrombosis, 2ed

The hemostasis laboratory has a vital role in the diagnosis and management of patients with familial and acquired haemorrhagic and thrombotic disorders. Its role in the monitoring of traditional anticoagulant therapy, as well as therapy using new anticoagulants, presents new challenges to the laboratory. This new edition addresses these important issues, as well as international guidelines for testing, the development of international standard materials, management of haemostasis testing from the laboratory to the point-of-care, and molecular genetic testing.

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Contents

۱ General quality planning in the hemostasis laboratory
۲ Hemostasis test validationperformanceand reference intervals: international recommendations and guidelines
۳ Causes of errors in medical laboratories
۴ International standards in hemostasis
۵ Sample integrity and preanalytical variables
۶ Internal quality control in the hemostasis laboratory
۷ External quality assessment in hemostasis: its importance and significance
۸ The unique challenges of hemostatic testing in children
۹ Initial evaluation of hemostasis: reagent and method selection
۱۰ Assay of factor VIII and other clotting factors
۱۱ Application of molecular genetics to the investigation of inherited bleeding disorders
۱۲ Detecting and quantifying acquired functional inhibitors in hemostasis
۱۳ Standardization of d-dimer testing
۱۴ Point-of-care testing in hemostasis
۱۵ Diagnostic assessment of platelet function
۱۶ Laboratory evaluation of heparin-induced thrombocytopenia
۱۷ Laboratory evaluation of von Willebrand disease: phenotypic analysis
۱۸ Laboratory analysis of von Willebrand disease: molecular analysis
۱۹ Quality issues in heritable thrombophilia testing
۲۰ Evaluation of antiphospholipid antibodies
۲۱ Monitoring heparin therapy
۲۲ Monitoring oral anticoagulant therapy with vitamin K antagonists
۲۳ Monitoring new anticoagulants