دانلود کتاب سلول های بنیادی در سم شناسی و پزشکی
Stem Cells in Toxicology and Medicine, 1ed

A comprehensive and authoritative compilation of up-to-date developments in stem cell research and its use in toxicology and medicine

Stem cells are undifferentiated cells in multicellular organisms capable of growing into various differentiated cell types. In recent years they have become an important research tool in biology, medicine and toxicology leading to a rapidly developing new scientific discipline. This monograph focuses on their use in toxicology and medicine at a level designed to take readers to the frontiers of research in this specialized area. The importance of this field of research is evidenced by the increasing number of articles published each year. This rapid development requires new means to report the results of ongoing studies. The contributions presented in this monograph represent a collaborative effort by international experts working in this emerging field of science.

The main aim of this book is to present state-of-the-art information on stem cells in one place. Therefore, I sincerely hope that this book will provide a comprehensive and authoritative source of current information on stem cells and prove useful to the investigators and students working in this scientific discipline throughout the world for years to come. It is my hope that the information presented in this book will serve as a stimulus to them. Also it is my hope that it will be of interest to a variety of other scientific disciplines including pharmacology, food, drug, and environmental sciences. In addition, this book should be of interest to the safety assessors and regulators of food, drug, environment, agriculture, and consumer products.

  • Presented by internationally recognized investigators in this exciting field of scientific research
  • Provides an insight into the current trends and future directions of research in this rapidly developing new field
  • A valuable and excellent source of authoritative and up-to-date information for researchers, toxicologists, drug industry, risk assessors and regulators in academia, industry and government

Contents

۱ Introduction
۲ Application of Stem Cells and iPS Cells in Toxicology
۳ Stem Cells: A Potential Source for High Throughput Screening in Toxicology
۴ Human Pluripotent Stem Cells for Toxicological Screening
۵ Effects of Culture Conditions on Maturation of Stem Cell‐Derived Cardiomyocytes
۶ Human Stem Cell‐Derived Cardiomyocyte In Vitro Models for Cardiotoxicity Screening
۷ Disease‐Specific Stem Cell Models for Toxicological Screenings and Drug Development
۸ Three‐Dimensional Culture Systems and Humanized Liver Models Using Hepatic Stem Cells for Enhanced Toxicity Assessment
۹ Utilization of In Vitro Neurotoxicity Models in Pre‐Clinical Toxicity Assessment
۱۰ A Human Stem Cell Model for Creating Placental Syncytiotrophoblast, the Major Cellular Barrier that Limits Fetal Exposure to Xenobiotics
۱۱ The Effects of Endocrine Disruptors on Mesenchymal Stem Cells
۱۲ Epigenetic Landscape in Embryonic Stem Cells
۱۳ The Effect of Human Pluripotent Stem Cell Platforms on Preclinical Drug Development
۱۴ Generation and Application of 3D Culture Systems in Human Drug Discovery and Medicine
۱۵ Characterization and Therapeutic Uses of Adult Mesenchymal Stem Cells
۱۶ Stem Cell Therapeutics for Cardiovascular Diseases
۱۷ Stem‐Cell‐Based Therapies for Vascular Regeneration in Peripheral Artery Diseases
۱۸ Gene Modified Stem/Progenitor‐Cell Therapy for Ischemic Stroke
۱۹ Role of Stem Cells in the Gastrointestinal Tract and in the Development of Cancer
۲۰ Cancer Stem Cells: Concept, Significance, and Management
۲۱ Stem Cell Signaling in the Heterogeneous Development of Medulloblastoma
۲۲ Induced Pluripotent Stem Cell‐Derived Outer-Blood‐Retinal Barrier for Disease Modeling and Drug Discovery
۲۳ Important Considerations in the Therapeutic Application of Stem Cells in Bone
۲۴ Stem Cells from Human Dental Tissue for Regenerative Medicine
۲۵ Stem Cells in the Skin

قیمت : 3500 تومان

لینک کوتاه : https://bookbaz.ir/?p=68936
نویسنده : Saura C. Sahu
ناشر : Wiley; 1 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 584
(ISBN) شابک : 1119135419
قیمت کتاب درآمازون : $146.64
حجم فایل : 10 MB

51yycU1w3cL._SX381_BO1,204,203,200_

۳۵۰۰ تـومان – خرید