A malignant tumor is an actively growing tissue, composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body, resulting in malignant cancer. Recent research suggests that…
Metastatic Carcinomas of Unknown Origin, by Mark R. Wick, MD, is the first comprehensive, fully illustrated discussion of the clinical features, pathologic attributes, and treatment approaches of metastatic carcinomas of unknown origin (MCUOs). More than 30,000 cases of MCUOs are…
Metastasis is responsible for a large burden of morbidity and mortality among cancer patients, and currently few therapies specifically target metastatic disease. Further scientific dissection of the underlying pathways is required to pave the way for new therapeutic targets. This…