دانلود کتاب روماتولوژی هاچبرگ (۲ جلدی) + ویدئو
Rheumatology, 2-Volume Set, 8ed + Video

Covering both the scientific basis of rheumatology and practical, clinical information for rheumatologists and trainees, Rheumatology, 8th Edition, remains a leading text in this fast-changing field. Dr. Marc Hochberg and his team of worldwide editors and authors keep you abreast of recent advances in the field― all in a user-friendly, accessible manner. Fully updated from cover to cover, this two-volume text is designed to meet the needs of all practicing and academic rheumatologists as well as arthritis-related health care professionals and scientists interested in rheumatic and musculoskeletal diseases.

• Covers the epidemiology, pathogenesis, clinical manifestations, therapeutic approach, and management of all major as well as rarely encountered rheumatic and musculoskeletal diseases.
• Discusses clinical examination, imaging principles, differential diagnosis, established and novel therapies, perioperative evaluation, pain management, basic science, and genetics of rheumatic and musculoskeletal diseases.
• Uses a consistent, logical, reader-friendly format with templated chapters, concise text, and large-scale, state-of-the-art illustrations for efficient visual reference.
• Contains new chapters covering pre-clinical disease and how to address these patients, common comorbidities in rheumatoid arthritis; emerging therapies for systemic sclerosis; immune mediated complications of checkpoint inhibitors; the epidemiology of COVID-19 and rheumatic and musculoskeletal diseases, emerging treatments for osteoarthritis, and big data analytics.
• Provides updates to key topics such as systems biology and its impact on our understanding of the pathogenesis of rheumatic and musculoskeletal diseases, the microbiome in rheumatic musculoskeletal diseases, how to manage chronic pain in the patient with a rheumatic disease, drugs and reproductive health, and emerging therapies for patients with RA, SLE, spondyloarthritis, inflammatory muscle disease, and vasculitis.
• Shares the knowledge and expertise of numerous new contributing authors, as well as new co-editor Dr. Désirée van der Heijde, who is an expert in psoriatic arthritis, spondyloarthritis, imaging, and clinical epidemiology.
• Provides access to concise videos depicting the use of ultrasound for diagnosis and treatment.

Contents

۱. The synovium
۲. The articular cartilage
۳. Bone structure and function
۴. Tendons and ligaments
۵. Biomechanics of peripheral joints and spine
۶. Scientific basis of pain
۷. Principles of innate immunity
۸. Principles of adaptive immunity
۹. Signal transduction in immune cells
۱۰. Cytokines
۱۱. Inflammation and its chemical mediators
۱۲. The complement system
۱۳. Osteoimmunology
۱۴. Joint tissue destruction and proteolysis
۱۵. Principles of tissue engineering and cell- and gene-based therapy
۱۶. Big Data analysis
۱۷. Principles and techniques in molecular biology
۱۸. Proteomics
۱۹. Metabolomics
۲۰. Epigenetics
۲۱. Precision medicine and pharmacogenomics in rheumatology
۲۲. The microbiome in rheumatic diseases
۲۳. Principles of epidemiology
۲۴. Principles of clinical outcome assessment
۲۵. Principles of health economics
۲۶. Principles of genetic epidemiology
۲۷. Interpreting the medical literature for the rheumatologist
۲۸. Ethics in clinical trials
۲۹. History and physical examination
۳۰. Laboratory tests in rheumatic disorders

More…

۱۸۰. The epidemiology of coronavirus disease 2019 (COVID-19) and rheumatic disease
۱۸۱. Epidemiology and classification of osteoarthritis
۱۸۲. Local and systemic risk factors for incidence and progression of osteoarthritis
۱۸۳. Clinical features of osteoarthritis
۱۸۴. Animal models of osteoarthritis
۱۸۵. Pathogenesis and pathology of osteoarthritis
۱۸۶. Genetics and epigenetics of osteoarthritis
۱۸۷. Imaging of osteoarthritis
۱۸۸. Assessment of the patient with osteoarthritis and measurement of outcomes
۱۸۹. Preclinical and early osteoarthritis
۱۹۰. Management of osteoarthritis
۱۹۱. Emerging treatments for osteoarthritis
۱۹۲. Epidemiology and classification of gout
۱۹۳. Etiology and pathogenesis of gout
۱۹۴. Clinical features of gout
۱۹۵. Management of gout and hyperuricemia
۱۹۶. Calcium pyrophosphate deposition disease (pseudogout)
۱۹۷. Basic calcium phosphate crystal deposition disease
۱۹۸. Epidemiology and classification of osteoporosis
۱۹۹. Clinical evaluation and clinical features of osteoporosis
۲۰۰. Pathophysiology of osteoporosis
۲۰۱. Biochemical markers of bone turnover in postmenopausal osteoporosis
۲۰۲. Management of osteoporosis
۲۰۳. Glucocorticoid-induced osteoporosis
۲۰۴. Osteomalacia, rickets, and renal osteodystrophy
۲۰۵. Paget disease of bone
۲۰۶. Diffuse idiopathic skeletal hyperostosis
۲۰۷. Neuropathic arthropathy
۲۰۸. Osteonecrosis
۲۰۹. Rheumatoid manifestations of endocrine and metabolic diseases and treatments
۲۱۰. Hemophilia-associated arthritis
۲۱۱. Rheumatologic manifestations of hemoglobinopathies
۲۱۲. Hemochromatosis
۲۱۳. Gaucher disease
۲۱۴. Digital clubbing and hypertrophic osteoarthropathy
۲۱۵. Miscellaneous arthropathies
۲۱۶. Heritable connective tissue disorders
۲۱۷. Hypermobility syndrome
۲۱۸. Bone tumors