دانلود کتاب هماتولوژی مولکولی
Molecular Hematology, 4ed

The new and fully-revised volume of molecular GRIBBEN biological techniques for practicing and trainee hematologists

Molecular Hematology is a comprehensive resource for hematologists to increase their understanding of the molecular basis of various blood diseases, their pathogeneses, and current and emerging molecular research and therapies. The impact of molecular research on the field of hematology is significant???molecular techniques are continuing to play a central role in the diagnosis and treatment of blood diseases. Molecular characterization of genes and proteins has increased our comprehension of the causes of hematological diseases and led to the development of new drug therapies and recombinant proteins.

Now in its fourth edition, Molecular Hematology has been thoroughly revised and updated to reflect current advances in molecular research. Chapters introduce and summarize specific disorders, such as hemophilia, anemia, and multiple myeloma, and illustrate the impact of molecular research on their diagnoses and treatments. Contributions written by respected clinicians and researchers offer accessible coverage of topics including lymphoma genetics, molecular coagulation and thrombophilia, platelet disorders, pharmacogenomics, and many others.

• Demonstrates the clinical relevance of molecular biology in hematology
• Provides overviews of recent advances in cancer cell biology, with an emphasis on leukemia and lymphoma
• Offers new and updated chapters written by an international team of experts
• Presents new full-color charts, graphs, and illustrations
• Includes access to a Wiley Companion Digital Edition providing search across the book, downloadable illustrations and notation tools

Molecular Hematology is an essential volume for both trainee and practicing hematologists and oncologists, molecular biologists, and research scientists working in the field of hematology.

Contents

۱ Beginnings: the molecular pathology of hemoglobin
۲ Stem cells
۳ The genetics of acute myeloid leukemias
۴ Molecular diagnostics and risk assessment in myeloid malignancies
۵ Molecular basis of acute lymphoblastic leukemia
۶ Chronic myeloid leukemia
۷ Myeloproliferative neoplasms
۸ Lymphoma genetics
۹ The molecular biology of chronic lymphocytic leukemia
۱۰ The molecular biology of multiple myeloma
۱۱ The molecular basis of bone marrow failure syndromes and red cell enzymopathies
۱۲ Anemia of chronic disease
۱۳ The molecular basis of iron metabolism
۱۴ Hemoglobinopathies due to structural mutations
۱۵ Molecular pathogenesis of malaria
۱۶ Molecular coagulation and thrombophilia
۱۷ The molecular basis of hemophilia
۱۸ The molecular basis of von Willebrand disease
۱۹ Platelet disorders
۲۰ The molecular basis of blood cell alloantigens
۲۱ Functions of blood group antigens
۲۲ Autoimmune hematological disorders
۲۳ Molecular therapeutics in hematology: gene therapy
۲۴ Pharmacogenomics
۲۵ History and development of molecular biology
۲۶ Cancer stem cells
۲۷ Molecular basis of transplantation

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