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Pathophysiology of Blood Disorders, 2ed

The acclaimed full-color review of the underlying principles of blood diseases and disorders – based on a Harvard Medical School hematology course

LANGE Pathophysiology of Blood Disorders, Second Edition is a well-illustrated, easy-to-absorb introduction to the physiological principles underlying the regulation and function of blood cells and hemostasis, as well as the pathophysiologic mechanisms responsible for the development of blood disorders. Featuring a strong emphasis on key principles, the book also covers diagnosis and management primarily within a framework of pathogenesis.

The organization and content of this book are based on a 3-week hematology course given to students in their second year at Harvard Medical School. All of the authors are lecturers in this course and many of the figures have been taken directly or adapted from their lectures.

FEATURES OF THE SECOND EDITION:

• NEW summary boxes with high yield points to remember
• All figures have been redrawn by a single artist for quality and consistency
• A more user-friendly presentation
• Each chapter includes learning objectives, and self-assessment questions with detailed explanations
• Numerous tables and diagrams encapsulate important information

Hailed for its uniformity of style, clarity, brevity, and high level of scientific rigor and clinical relevance, LANGE Pathophysiology of Blood Disorders, Second Edition will prove valuable to medical students, as well as physicians at all stages of their training.

About the Author

Frank Bunn, MD is Professor of Medicine at Harvard Medical School, and is a former President of the American Society of Hematology

Jon Aster, MD is an educator at Harvard Medical School who specializes in anatomic pathology and clinical pathology. Dr. Aster is also affiliated with Brigham and Women’s Hospital.

Contents

۱. Introduction to Blood and Hematopoietic Tissues
۲. Hematopoiesis
۳. Overview of the Anemias
۴. Anemias Due to Bone Marrow Failure or Infiltration
۵. Iron Homeostasis: Deficiency and Overload
۶. Megaloblastic Anemias
۷. Anemias Associated With Chronic Illness
۸. Thalassemia
۹. Sickle Cell Disease
۱۰. Inherited Hemolytic Disorders of the Red Cell Membrane and Red Cell Metabolism
۱۱. Acquired Hemolytic Anemias
۱۲. Erythrocytosis
۱۳. Overview of Hemostasis
۱۴. Platelet Disorders
۱۵. Inherited Coagulation Disorders
۱۶. Acquired Coagulation Disorders
۱۷. Thrombotic Disorders
۱۸. Leukocyte Function and Nonmalignant Leukocyte Disorders
۱۹. Introduction to Hematologic Malignancies
۲۰. Myeloproliferative Neoplasms and Myelodysplastic Syndromes
۲۱. Acute Leukemias
۲۲. Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemias
۲۳. Hodgkin Lymphoma
۲۴. Multiple Myeloma and Related Disorders
۲۵. Blood Transfusion
۲۶. Hematopoietic Stem Cell Transplantation