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Advances in Malignant Hematology, 1ed

Advances in Malignant Hematology captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward malignant hematology. This recent and ongoing explosion of knowledge has not previously been captured and utilized to its full capacity due to its diffuse distribution over the internet and research publications.

This comprehensive book is written by experts from the American and European continent, sharing their current thoughts and knowledge on the pathobiology of malignant hematological diseases, their current treatment strategies and future developments.

The book is divided into five sections:

• Hematopoiesis
• Myeloid Malignancies
• Lymphoid Malignancies
• Plasma Cell Disorders
• Bone Marrow Transplantation and Quality of Life

There was a time when the practicing hematologist could only offer treatment for the symptoms of malignant disease states. Now, treatment attempts are being offered to attack and eradicate diseases at their molecular level. In some instances this has helped to achieve a near cure, and perhaps a complete cure in the near future, for some of the hematological malignancies.

Advances in Malignant Hematology provides significant help in the battle against hematologic cancer and will be valuable to hematologists in training and in practice.

Review

Contents

۱ Normal and Malignant Hematopoiesis
۲ The Leukemia Genome
۳ Myeloproliferative Neoplasms
۴ Molecular Pathogenesis of BCR-ABL in Chronic Myeloid Leukemia
۵ Standard Management of Patients with Chronic Myeloid Leukemia
۶ The Molecular Biology of Acute Myeloid Leukemia
۷ Acute Myeloid Leukemia
۸ Acute Promyelocytic Leukemia
۹ A Pluralistic Approach to the Study of Myelodysplastic Syndromes: Evolving Pathology of the Seed via the Soil
۱۰ Myelodysplastic Syndrome: A Review of Current Care
۱۱ Supportive Care in Myelodysplastic Syndrome
۱۲ Molecular Biology of Chronic Lymphoproliferative Disorders
۱۳ Chronic Lymphocytic Leukemia
۱۴ Acute Lymphoblastic Leukemia
۱۵ Large Granular Lymphocyte Leukemia
۱۶ Hairy Cell Leukemia
۱۷ Molecular Basis of B-cell Lymphomas
۱۸ Non-Hodgkin Lymphomas
۱۹ Hodgkin Lymphoma
۲۰ Multiple Myeloma: Molecular BiologyDiagnosis and Treatment
۲۱ Waldenstro¨m’s Macroglobulinemia
۲۲ Primary Systemic Amyloidosis (AL)
۲۳ Advances in Allogeneic Hematopoietic Cell Transplantation: Progress in Transplantation Technology and Disease-Specific Outcomes
۲۴ Quality of Life after the Diagnosis of Hematological Malignancies