دانلود کتاب دستورالعمل ضد میکروبی ۲۰۲۴
Antimicrobial Guidelines 2024 3rd Edition

The majority of hospitalized patients receive antimicrobials for therapy or prophylaxis during their inpatient stay. It has been estimated that at least fifty percent of hospitalized patients receive antibiotics unnecessarily. Reasons include inappropriate prescribing for antibiotic prophylaxis, inappropriate choice of empiric antibiotics, continuation of empiric therapy despite negative cultures in a stable patient, and a lack of awareness of susceptibility patterns of common pathogens. Over-prescribing not only increases the cost of health care, but may result in emergence of resistant bacteria, superinfection with opportunistic fungi, as well as increase the likelihood of adverse drug reactions. On the other hand, not prescribing (when there is an urgent need) may also lead to serious consequences.

In this edition of the guideline we reveiwed the empirical and targeted therapy, management approaches of neonatal and pediatric infections and the recommended dosage. Approaches to prevention of some perinatal infections were added in this edition.

The recommendations in this guideline are based on the current local susceptibility pattern and Children hospital atibiogram. We will review these guidelines regularally and will adjust our antimicrobial choices according to the in vitro susceptibility data. Our mission is to provide the most cost-effective antimicrobial agents to our patients.

Contents

Introduction
Antimicrobial Stewardship
Antimicrobial Susceptibility Report -2023
Initial empirical antibiotic therapy in children
Recommended therapy for specific bacterial infections
Recommended antiviral therapy for specific viral infections
Antifungal therapy for specific fungal infections
Antiparasitic therapy for specific parasitic infections
Clinical approach to common childhood infections
Prevention and Management approach perinatal infections
Surgical Prophylaxis
Antimicrobial dosage in neonates
Antimicrobial dosage for older infants and children
Intraventricular/lntrathecal dosage
Dosage adjustment of antimicrobials in patients with impaired renal function
Intraperitoneal antibiotic dosing in PD-related peritonitis