دانلود کتاب آسیب شناسی عملی کلیه: یک رویکرد تشخیصی
Practical Renal Pathology: A Diagnostic Approach, 1ed

Anatomic pathology is a pattern-based discipline; we recognize the patterns cells make on a cytology smear preparation, the architecture of a tumor, and the pattern of fibrosis in a kidney biopsy from a hypertensive patient. One might question, though, how one textbook can encompass the patterns of injury within the kidney wrought by hypertension, infection, renal cell carcinoma, polycystic kidney disease, thrombosis, ANCA antibodies, and amyloid and hereditary nephritis, for example, into eight patterns of injury. Well read on; we aim to show you. Pattern-based diagnostic approach: As you examine an H&E stained section of kidney at low magnification you notice certain variations from the normal architecture. For instance, at scanning magnification you may observe a nodular process involving the parenchyma.

The nodules appear solid, not cystic, and are reasonably well demarcated. So within just a few seconds you have narrowed your differential diagnosis to a nodular process involving the renal parenchyma. At higher magnification you see that the nodule is composed of spindled cells with a few thick-walled vessels, admixed with areas of adipose tissue. You conclude that the nodule is an angiomyolipoma. You also see that the surrounding parenchyma contains a few cysts, and you begin to wonder if the patient might have tuberous sclerosis. Focusing on the glomeruli, you again notice a nodular pattern; however, these nodules are within the glomerular mesangium, and you think that perhaps the patient has diabetes mellitus. So by using a pattern-based approach you have formulated the highly probable diagnosis of angiomyolipoma in a patient with tuberous sclerosis who is also diabetic.

Practical Renal Pathology helps you apply a systematic pattern recognition approach to achieve more accurate diagnoses of both neoplastic and non-neoplastic diseases of the kidneys. This volume in the Pattern Recognition Series helps you to efficiently and confidently evaluate even the most challenging histologic specimens.

• Compare your specimens to commonly seen patterns, categorize them accordingly, and turn directly to in-depth diagnostic guidance using the unique, pattern-based Visual Index at the beginning of the book.
• Assess key pathologic and clinical aspects of both neoplastic and non-neoplastic conditions with over 750 high-quality, full-color images that help you evaluate and interpret biopsy samples.
• Benefit from expert guidance in key areas such as renal biopsy interpretation, handling of nephrectomy specimens, pathology relevant to renal transplantation, and pathology of unusual renal neoplasms.
• Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis.

Contents

۱ Embryology and Normal Anatomy of the Kidney
۲ Renal Cystic Diseases
۳ Renal Biopsy Interpretation:
۴ Glomerular Diseases— Primary
۵ Glomerular Diseases— Secondary
۶ Glomerular Diseases— Hereditary
۷ Tubulointerstitial Diseases
۸ Vascular Diseases
۹ Pathology of Kidney Transplantation
۱۰ Optimal Specimen Handling and Ancillary Studies:
۱۱ Pediatric Renal Neoplasms
۱۲ Epithelial Neoplasms of the Renal Cortex
۱۳ Nonepithelial Neoplasms of the Kidney
۱۴ Unusual Renal Neoplasms
۱۵ Renal Pelvic and Ureteral Tumors and Tumors Frequently Found in the Renal Medullary Region