دانلود کتاب تنظیم ژن و درمان سرطان
Gene Regulation and Therapeutics for Cancer, 1ed

Differential gene regulation and targeted therapy are the critical aspects of several cancers. This book covers specific gene regulation and targeted therapies in different malignancies. It offers a comprehensive assessment of the transcriptional dysregulation in cancer, and considers some examples of transcriptional regulators as definitive oncogenic drivers in solid tumors, followed by a brief discussion of transcriptional effectors of the programs they drive, and discusses its specific targets. Most targeted therapeutics developed to date have been directed against a limited set of oncogenic drivers, exemplified by those encoding cell surface or cytoplasmic kinases that function in intracellular signaling cascades.

Review

Contents

۱. Programmed Death 1Receptor (PD-l)-mediated Immunomodulatory Effects in Pancreatic Cancer
۲. Nuclear Factor Kappa-B: Bridging Inflammation and Cancer
۳. The S100A7/8/9 Proteins: Novel Biomarker and Therapeutic Targets for Solid Tumor Stroma
۴. Nuclear Receptor Coactivators: Mechanism and Therapeutic Targeting in Cancer
۵. Liquid Biopsies for Pancreatic Cancer: A Step Towards Early Detection
۶. Targeting Subgroup-specific Cancer Epitopes for Effective Treatment of Pediatric Medulloblastoma
۷. Aberrant Methylation of UC Promoters in Human Pancreatic Ductal Carcinomas
۸. Receptor Tyrosine Kinase Signaling Pathways as a Goldmine for Targeted Therapy in Head and Neck Cancers
۹. Molecular Drivers in Lung Adenocarcinoma: Therapeutic Implications
۱۰. Molecular Mediator of Prostate Cancer Progression and Its Implication in Therapy
۱۱. Therapeutic Options for Prostate Cancer: A Contemporary Update
۱۲. Regulation and Targeting of MUCINS in Pancreatic Cancer
۱۳. Targeted Therapy for Cancer Stem Cells