دانلود کتاب سمیت بیهوشی
Anesthetic Toxicity, 1ed

This text is a source of information on the toxicity of anaesthetic agents. The editors define toxicity in a broad sense to mean an adverse effect, whether that effect is the result of pharmacological, toxicological, physiological, or other mechanisms. They bring together reviews by experts in the disciplines concerned – including biochemistry, genetics, and immunology – involved in current research on these adverse effects.; The initial chapters provide an understanding of the factors responsible for toxicity, and the ways in which the adverse effects of anaesthetics can be investigated. Subsequent chapters cover topics such as: hepatotoxicity; nephrotoxicity; malignant hyperthermia triggered by anaesthetics; pulmonary effects of anaesthesia; toxicity of local anaesthetic agents; toxicity of nitrous oxide; immunosuppression in the postoperative period; and reproductive and developmental toxicity of anaesthetics. Many of the contributors offer insights into the anaesthetics and their interactions, such as the immunological effects of anaesthesia and the impact of pharmacogenetics.

Contents

۱. Anesthetic Toxicity: An Overview
۲. Animal Use in Toxicity Evaluation
۳. Principles of Epidemiology for Evaluation of Anesthetic Toxicity
۴. Metabolism of the Volatile Anesthetics
۵. Hepatotoxicity of Halogenated Anesthetics
۶. Nephrotoxicity of Volatile Anesthetic Agents
۷. Toxicity of Local Anesthetic Agents
۸. Toxicity of Nitrous Oxide
۹. Reproductive and Developmental Toxicity of Anesthetics in Animals
۱۰. Reproductive and Developmental Toxicity of Anesthetics in Humans
۱۱. Pharmacogenetics and Anesthetic Toxicity
۱۲. Malignant Hyperthermia Triggered by Anesthetics
۱۳. Immunosuppression in the Postoperative Period
۱۴. Pulmonary Effects of Anesthesia
۱۵. Biomarkers of Anesthetic Toxicity