دانلود کتاب علوم اعصاب برای پزشکان: فرآیندهای اساسی، مدارها، مکانیسم های بیماری و پیامدهای درمانی
Neuroscience for Clinicians: Basic Processes, Circuits, Disease Mechanisms, and Therapeutic Implications, 1ed

Neuroscience for Clinicians is a comprehensive and clinically relevant survey of emerging concepts on the organization and function of the nervous system and neurologic disease mechanisms. By emphasizing how genetic, molecular, and cellular processes and their interactions control the function of the nervous system, the work will help clinicians understand emerging concepts about the mechanisms of neurologic disorders including neurodegeneration, channelopathies, and synaptic dysfunction that provide potential therapeutic targets .

This single-authored textbook utilizes ample figures and tables throughout in order to facilitate retention of the core concepts presented. Divided into 5 sections, the first section includes chapters focused on basic cellular processes. Section 2 includes chapters focused on cell communication while Section 3 focuses on the neuronal microenvironment. The fourth section focuses on the organization and interactions of circuits in the cortex, thalamus, and brainstem, underlying behavioral states such as sleep, sensory processing, and motor control. The fifth section addresses mechanisms of pain and neural control of survival. And the final section covers concepts on mechanisms of emotion, social behavior, memory, language, and executive functions with emphasis on dementia and behavioral disorders.

Review

Contents

۱. Overview: Cellular Components of the Nervous System and Disease Mechanisms
۲. Organization of Cell Membranes
۳. Intracellular Signaling
۴. DNA: Epigenetic Control of Transcription and Repair Mechanisms
۵. Messenger RNA Metabolism
۶. Proteostasis
۷. Vesicular Trafficking
۸. Cytoskeleton
۹. Axonal Transport
۱۰. Axon and Myelin
۱۱. Mitochondria and Energy Metabolism
۱۲. Mechanisms of Cell Death and Axonal Degeneration
۱۳. Growth Factors, Survival, and Regeneration
۱۴. Ion Channels and Channelopathies
۱۵. Synaptic Transmission and Presynaptic Synaptopathies
۱۶. Neurotransmission, Neuromodulation, and Plasticity
۱۷. Glutamatergic Transmission and Synaptopathies
۱۸. Inhibitory Amino Acid Neurotransmission and Synaptopathies
۱۹. Cholinergic Transmission
۲۰. Monoaminergic Systems
۲۱. Astrocytes and Astrocyte–Neuron Interactions
۲۲. Microglia and Neuroinflammation
۲۳. Microenvironment in the Central Nervous System
۲۴. Neocortical Organization and Circuits
۲۵. Hippocampal and Amygdala Circuits
۲۶. Thalamus and Thalamocortical Interactions
۲۷. Sleep–Wake Cycle and Circadian Rhythms
۲۸. Behavioral State Control
۲۹. Sensory Processing
۳۰. Motor Cortex
۳۱. Spinal Motor Control
۳۲. Brainstem Mechanisms of Motor Control
۳۳. Cerebellar Circuits
۳۴. Basal Ganglia Circuits
۳۵. Peripheral and Spinal Mechanisms of Nociception
۳۶. Central Processing and Modulation of Pain
۳۷. Autonomic Control and Survival
۳۸. Homeostasis and Adaptation
۳۹. Emotion and Social Cognition
۴۰. Episodic Memory
۴۱. Language
۴۲. Executive Control