دانلود کتاب شیمی درمانی ضد میکروبی
Antimicrobial Chemotherapy, 7ed

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents.

The fully revised and updated seventh edition of Antimicrobial Chemotherapy is an essential guide to the principles of antimicrobial chemotherapy, the problem of resistance and its control through policies, antimicrobial stewardship and surveillance. The book provides an aid to informed, rational prescribing for common bacterial, fungal, parasitic and viral infections.

Divided in five parts, the book cover issues specific to both the developed and developing world. Part 1 ‘General property of antimicrobial agents’ discusses mechanisms of action and resistance to antibacterial, antifungal antiprotozoal, antiviral, and antiviral agents. Part 2 ‘Resistance to antimicrobial agents’ provides guidance about the problem of resistance, mechanisms of acquired resistance and genetics of resistance. Part 3 ‘General principles of usage of antimicrobial agents’ analyses the use of the laboratory, general principles of the treatment of infection, dosing in special groups (extremes of age, pregnancy, obesity), safe prescribing, prophylaxis and the role of policies in antimicrobial stewardship. Part 4 ‘Therapeutic use of antimicrobial agents’ provides advice about the treatment of common infections which are described by anatomical. There are also chapters on the management of mycobacterial disease, viral infections, HIV/AIDS and parasitic infections. The final part of the book analyses the development and marketing of antimicrobial drugs.

This seventh edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs.

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Contents

۱ Mechanisms of action and resistance to modern antibacterials, with a history of their development
۲ Inhibitors of bacterial cell wall synthesis
۳ Inhibitors of bacterial protein synthesis
۴ Synthetic antibacterial agents and miscellaneous antibiotics
۵ Antiviral agents
۶ Antiretroviral agents
۷ Drugs used in the treatment of viral hepatitis
۸ Antifungal agents
۹ Antiprotozoal and anthelminthic agents
۱۲ Resistance to antimicrobial agents
۱۰ The problem of resistance
۱۱ The genetics and mechanisms of acquired resistance
۱۳ General principles of usage of antimicrobial agents
۱۲ Laboratory investigations and the treatment of infection
۱۳ General principles of the treatment of infection
۱۴ Pharmacokinetic and pharmacodynamic principles
۱۵ Prescribing in special groups: effects of ager pregnancy, body weight,and hepatic and renal impairment
۱۶ OPAT: outpatient parenteral antimicrobial therapy
۱۷ Adverse drug reactions, and patient safety
۱۸ Chemoprophylaxis and immunization
۱۹ Guidelines, formularies, and antimicrobial policies
۲۰ Antimicrobial stewardship, surveillance of antimicrobial consumption, and its consequences
۲۱ Respiratory tract infections
۲۲ Topical use of antimicrobial agents
۲۳ Urinary tract infections
۲۴ Sexually transmitted infections
۲۵ Gastrointestinal infections
۲۶ Serious bacterial bloodstream infections
۲۷ Bone and joint infections
۲۸ Infections of the central nervous system
۲۹ Skin and soft-tissue infections
۳۰ Tuberculosis and other mycobacterial diseases
۳۱ Infections in immunocompromised patients, including HIV/AIDS
۳۲ Viral infections
۳۳ Management of HIV infection
۳۴ Treatment of chronic viral hepatitis
۳۵ Parasitic disease
۳۶ The development and marketing of antimicrobial drugs