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The Autoimmune Diseases, 6ed
The Autoimmune Diseases, Sixth Edition, emphasizes the “3 P’s” of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data (“omics”) coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments.
The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.
- Gives a thorough and important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and its therapy
- Provides thorough, up-to-date information on specific diseases, along with clinical applications in an easily found reference for clinicians and researchers interested in certain diseases
- Keeps readers abreast of current trends and emerging areas in the field
- Ensures that content is not only up-to-date, but applicable and relevant
- Includes new, updated chapters that emphasize hot topics in the field, e.g., research on auto inflammatory diseases and autoimmune responses following cancer immunotherapy
Review
Presents an essential resource for basic and clinical scientists committed to the study, diagnosis and treatment of autoimmune disorders
Contents
۱. Prelude: Historical introduction to autoimmunity and autoimmune disease
۲. Structural and Functional Aspects of the Innate and Adaptive Systems of Immunity
۳. General Features of Autoimmune Diseases
۴. Antigen Presentation, Dendritic Cells, and Autoimmunity
۵. T cells and their subsets
۶. Role of Th1 Th2 Th17 Cells in Autoimmunity
۷. Tolerance and Autoimmunity: T Cells
۸. Regulatory T Cells
۹. B Cells and Autoimmunity
۱۰. Immunological memory T cells
۱۱. Immunological memory B cells 12. Apoptotic Cells as a Source of Autoantigens
۱۳. Effector Mechanisms of Autoimmunity: Antibodies and Immune Complexes
۱۴. Functional Effects of Autoantibodies
۱۵. Cytokine Chemokines
۱۶. Signaling Pathways in T and B Lymphocytes
۱۷. HLA Genetics and Autoimmunity
۱۸. Non HLA Genetics
۱۹. AIRE related Autoimmunity
۲۰. Immune Deficiencies and Autoimmunity
۲۱. Infections and Autoimmunity
۲۲. Noninfectious Environmental Agents and Autoimmunity
۲۳. Sex, Pregnancy and Autoimmunity
۲۴. Animal Models of Autoimmune Disease
۲۵. Systemic Lupus Erythematosus
۲۶. Systemic Sclerosis, Scleroderma
۲۷. Antiphospholipid Syndrome
۲۸. Sjogren Syndrome
۲۹. Rheumatoid Arthritis
۳۰. Spondyloarthritis and Chronic Idiopathic Arthropathies
۳۱. Myositis
۳۲. Thyroid Disease
۳۳. Type 1 Diabetes
۳۴. Adrenalitis
۳۵. Polyendocrine Syndromes
۳۶. Gastritis and Pernicious Anemia
۳۷. Hypophysitis
۳۸. Hemolytic Anemia
۳۹. Thrombocytopenic Purpura
۴۰. Neutropenia
۴۱. Aplastic Anemia
۴۲. Clotting Disorders
۴۳. Multiple Sclerosis
۴۴. Peripheral Neuropathy
۴۵. Myasthenia Gravis
۴۶. Ocular Disease
۴۷. Inner Ear Disease
۴۸. Celiac Disease
۴۹. Inflammatory Bowel Diseases: Ulcerative Colitis and Crohn’s Disease
۵۰. Chronic Hepatitis
۵۱. Primary Billiary Cirrhosis
۵۲. Primary Sclerosing Cholangitis
۵۳. Pancreatitis
۵۴. Bullous Skin Diseases: Pemphigus and Pemphigoid
۵۵. Non-Bullous Skin Diseases: Alopecia, Vitiligo, Psoriasis and Urticaria
۵۶. Kidney Disease: Goodpasture’s Disease, Lupus Nephritis, ANCA-Associated Glomerulonephritis
۵۷. Orchitis and Male Infertility
۵۸. Oophoritis
۵۹. Rheumatic Heart Disease
۶۰. Myocarditis and Dilated Cardiomyopathy
۶۱. Necrotizing Arteritis and Small Vessel Vasculitis
۶۲. Large and Medium Vessel Vasculitides
۶۳. Autoimmune Disorders of the Lung
۶۴. Paraneoplastic Diseases
۶۵. Antibody-Associated Neurological Diseases
۶۶. Autoinflammatory and other Related Diseases
۶۷. Autoantibody Assays, Testing, and Standardization
۶۸. Prediction of Autoimmune Disease
۶۹. Emerging Therapies for Autoimmune Diseases
۷۰. Postlude
لینک کوتاه : https://bookbaz.ir/?p=219058
نویسنده : Noel R. Rose
ناشر : Academic Press; 6th edition
سال انتشار : 2020
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 1450
(ISBN) شابک : 0128121025
قیمت کتاب درآمازون : $239.97
حجم فایل : 20 MB