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Fast Facts: Inflammatory Bowel Disease, 5ed

Ulcerative colitis and Crohn’s disease, referred to collectively as inflammatory bowel disease (IBD), are chronic debilitating disorders. IBD, particularly Crohn’s disease, is increasing everywhere, most notably in the Western world where about 1 in 200 people now has the condition. This highly readable, ‘zippy’ fourth edition of Fast Facts: Inflammatory Bowel Disease provides succinct yet thorough information that will aid early recognition of these disorders and their complications, alongside practical holistic management advice.

Inflammatory bowel disease (IBD) comprises two idiopathic chronic relapsing and remitting inflammatory disorders of the gastrointestinal tract: ulcerative colitis and Crohn’s disease. The swift pace of advances in knowledge, understanding and innovation in the treatment of IBD has driven the need for this new edition.

Here, we continue to emphasize the disturbances of host immune and environmental interactions in the etiopathogenesis of these disorders, in particular the genetically determined disturbances of host–microbe interactions. We also highlight recent improvements in our understanding of how best to use immunomodulatory and biological drugs, alone and in combination, and include the most recent innovations in this area. In the future, increasing efforts will be made to offer personalized treatment to each patient. The selection of specifc drugs only after detailed assessment of the genotype and other features of the individual will help us to identify who will respond well and who will respond badly, and thus enable us to use therapeutic agents more appositely.

Contents

CHAPTER 1: Etiopathogenesis
CHAPTER 2: Clinical features and intestinal complications
CHAPTER 3: Extraintestinal manifestations and complications
CHAPTER 4: Diagnosis
CHAPTER 5: Drugs used to treat inflammatory bowel disease
CHAPTER 6: Principles of management
CHAPTER 7: Medical management of ulcerative colitis
CHAPTER 8: Medical management of Crohn’s disease
CHAPTER 9: Surgery
CHAPTER 10: IBD in pregnancyr childhood and old age
CHAPTER 11: Prognosis