دانلود کتاب سم شناسی پانکراس
Toxicology Of The Pancreas

Features

• Includes data on both exocrine and endocrine pancreas and emphasizes the importance of the interaction between the two tissues
• Covers the little understood vascular structure of the pancreas vital in regulating the normal function of some pancreatic cell elements involved in the regulation of normal enzyme secretion
• Highlights components of pancreatic tissue that appear to be of significant importance in understanding toxicological events
• Explores the pancreas’ drug metabolizing enzyme system and significance of the presence of cytochrom p450 and GST metabolizing enzyme, which vary in type and quantity between the individual pancreatic cells
• Includes examples of environmental factors that can adversely affect the pancreas and lead to serious consequences

Summary

The increased incidence of pancreatic cancer in the Western world and its grave prognosis has resulted in an urgency for research in this area. Until now the available data on toxicology of the pancreas has been few and fragmentary, scattered throughout the literature. A benchmark volume, Toxicology of the Pancreas pulls together information in this neglected area of toxicological research and highlights fundamental research performed in the last ten years.

Leaders in the field discuss important structures, the detoxification and toxification process at the cellular and sub-cellular level, the distribution of phase 1 and phase 2 drug-metabolizing enzymes and their role in pancreatic disease, and the role of diet and toxicants on pancreatic disease. The book also covers the role of altered genes in the integrity of the pancreas and explores comparative toxicology in humans and in the lab species used in testing.

Illustrated with histological, electron microscopical, and immunohistochemical formats, this book provides a comprehensive and novel presentation of biological and toxicological data. It stands alone as a reliable resource of information easily accessible to professionals in different disciplines.