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Basic Concepts in Medicinal Chemistry 3rd Edition

Designed to help students incrementally build their knowledge of fundamental concepts of medicinal chemistry and their applications to therapeutic decisions, it is progressively organized. Specific sections of the text have been updated to make potentially confusing concepts easier to understand. Numerous examples and review questions further reinforce learning and analytical skills.

This updated and expanded edition of the popular textbook, Basic Concepts in Medicinal Chemistry, has been enhanced with new subject material, numerous self-assessment tools, and special features to advance and strengthen the learning process.

New in the Third Edition

• Enhanced explanations, discussions, and examples in many key chapters
• Additional summary tables to help readers better select the proper drug binding interaction
• Expanded discussion on Pharmacogenomics, including multiple specific examples
• Updated examples throughout the text to include a wider range of drugs and drug classes
• Increased focus on application of concepts to therapeutic decisions and pharmacy practice

Contents

Chapter 1: Introduction
Chapter 2: Functional Group Characteristics and Roles
Chapter 3: Identifying Acidic and Basic Functional Groups
Chapter 4: Solving pH and pKa Problems
Chapter 5: Salts and Solubility
Chapter 6: Drug Binding Interactions
Chapter 7: Stereochemistry and Drug Action
Chapter 8: Drug Metabolism
Chapter 9: Structure Activity Relationships and Basic Concepts in Drug Design
Chapter 10: Whole Molecule Drug Evaluation