دانلود کتاب بیماریهای گرمسیری نادیده گرفته شده: کشف و توسعه دارو
Neglected Tropical Diseases: Drug Discovery and Development, 1ed

A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people.

Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases. The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation.

The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases. Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites. For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies. The book also includes information on potential drug compounds derived from natural products. This important book:

-Ties together information from different sources for developing novel treatsments forneglected tropical diseases
-Is aligned with WHO?s initiative to eradicate tropical diseases
-Outlines current and potential drugs for treating tropical diseases
-Provides a standard reference for the entire field

Written for medicinal chemists, pharmaceutical chemists, pharmaceutical industry, virologists, parasitologists, and specialists on tropics medicine, Neglected Tropical Diseases offers an essential guide and a systematic reference for the development of successful treatments for 12 crippling infectious diseases.

About the Author

Contents

۱ Drug Discovery Strategies for Neglected Tropical Diseases: Repurposing Knowledge, Mechanisms and Therapeutics to Increase Discovery Efficiency
۲ Toward Antiviral Therapies for the Treatment of Zika Virus Infection: Lessons Learned from Dengue Virus
۳ Developing Therapeutics for Ebola Virus Disease: A Multifaceted Approach
۴ Designing Drugs to Target Trypanosoma cruzi, the Etiological Agent of Chagas Disease: When Chemistry needs Biology
۵ Drug Discovery and Development for Human African Trypanosomiasis
۶ Discovery of Drugs for Leishmaniases: A Progress Report
۷ Onchocerciasis Drug Discovery
۸ Drug Discovery and Development for Schistosomiasis
۹ Soil-transmitted Helminthiasis – Challenges with Discovery of Novel Anthelmintics
۱۰ Drug Discovery and Development for the Treatment of Echinococcosis, Caused by the Tapeworms Echinococcus granulosus and Echinococcus multilocularis
۱۱ New Insights into the Treatment of Foodborne Trematode Infections
۱۲ Buruli Ulcer
۱۳ Drug Discovery and Development for Leprosy