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Geha’ Case Studies in Immunology: A Clinical Companion, 6ed

Case Studies in Immunology, Sixth Edition, presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. The case histories illustrate essential points about the mechanisms of immunity and describe immunological problems seen in the clinic. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. Case Studies in Immunology highlights major common disorders of immunity, including hypersensitivity types I-IV, immune deficiencies, and autoimmune disorders. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the specific disorders. An end-of-case summary, questions, and discussion points conclude each case.

Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway’s Immunobiology, Eighth Edition. A marginal icon in Janeway’s Immunobiology provides the reader with a link to the relevant Case Study, where the science is applied in a clinical setting.

The book includes a total of 53 cases. The Sixth Edition is extensively revised and updated and includes ten new cases:

• DiGeorge Syndrome
• Hemophagocytic Lymphohistiocytosis
• Chediak-Higashi Syndrome
• Hyper IgE Syndrome
• Ataxia Telangiectasia
• Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome
• Severe Congenital Neutropenia
• Recurrent Herpes Simplex Encephalitis
• Systemic Onset Juvenile Idiopathic Arthritis
• Crohn’s Disease

The book is full of high yield tables and figures. I think is useful for the USMLE but only after reading another source like Medical Microbiology and Immunology Examination and Board Review or from Kaplan. It also has many interesting questions at the end of each case. Is a very well organized text; don’t think that you’re going to see only cases and questions, NOT it begins each case with the basic concepts in that topic, then the case, and detail explanations of the disease, and some questions. If you don’t have the time to read the complete text, I think that you can do very well just with the tables and Figures(full color), it contains some MRIs, CT, x-rays, and electron microscopies. Most of the cases are about the most high yield diseases (immunologic diseases) found in the USMLE and some are about diseases that you may have never heard but that may be tested as gene knock-outs or mutations cases. Is useful for USMLE Step 1,2 and 3 since it gives you basic concepts, pathogenesis and explanations about treatment.