دانلود کتاب هیپوپیگمانتاسیون
Hypopigmentation, 1ed

There are many disorders of a lack of pigmentation in the skin, with different causations and effects, of which vitiligo is only the best known; this comprehensive text from international experts will enable clinicians to diagnose the full range of these conditions and suggest the most effective management options for their patients.

The skin is the most visible organ, and dyschromias and disorders of pigmentation may be a common cause of significant psychological burden in affected individuals. Hypopigmentation of the skin is characterized clinically by areas of “offwhite” color that is lighter compared to the surrounding normal skin, or by areas of complete loss of pigmentation characterized by absolute white color. Hypopigmentation may reflect cutaneous diseases such as vitiligo or mosaic or post-inflammatory hypopigmentation, or be a marker of underlying systemic disorders and complex genetic syndromes including tuberous sclerosis, albinism, piebaldism, Waardenburg syndrome, and other rare disorders. Moreover, hypopigmentation may be a sign of cutaneous T-cell lymphoma or be induced by drugs, including cancer immunotherapy such as anti-PD-1 agents.

This comprehensive illustrated text from international experts aims to enable clinicians to diagnose and treat the full range of these conditions in children and in adults by discussing detailed clinical clues and presenting signs and explaining the approach to management.

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