دانلود کتاب فشار خون بالا ریوی آکسفورد
Pulmonary Hypertension, 1ed

High pressure in the lungs, or pulmonary hypertension, is most commonly due to smoking-related lung disease and conditions affecting the left heart, for example, high blood pressure in the arteries, faulty heart valves, and a weakened heart muscle. Pulmonary arterial hypertension (PAH), is a rare and complex disease, associated with many different medical conditions, which is caused by a growth of cells lining the inside of the lung arteries, resulting in high pressure in areas of the body. Both conditions lead to strain and potential failure of the right heart, and therefore awareness and early diagnosis of the condition is needed to lead to better outcomes: however this depends on education of all specialists and primary care clinicians about PAH.

This practical handbook covers both PH and PAH, providing information required by the wide range of clinicians who will encounter these conditions, including cardiologists, respiratory physicians, rheumatologists, specialists in liver and AIDS medicine, and hematologists. It covers what it is, who it is likely to affect, how it is diagnosed, including the pitfalls of the various diagnostic tests, the different and evolving forms of treatment, long term management of this often devastating chronic disease, and the crucial role of multidisciplinary management in optimizing clinical care of these patients who usually have multi-system diseases. It also covers the up new classification for both PH and PAH, and new drugs that have recently become available.

About the Author

Contents

۱. History of pulmonary hypertension (PH) and the circulation
۲. Definitions of PH and PAH
۳. The Dana Point (2008) clinical classification of PH
۴. Prognosis of PAH
۵. Pathology of PAH
۶. Pathology of pulmonary veno-occlusive disease and pulmonary capillary haemangiomatosis
۷. Pathology of PH due to left heart disease
۸. Pathology of PH due to lung diseases and/or hypoxia
۹. Pathology of chronic thromboembolic pulmonary hypertension
۱۰. Pathology of PH with unclear and/or multifactorial mechanisms
۱۱. Pathobiology of PAH
۱۲. Pathophysiology of PH in non-PAH groups
۱۳. Inflammation, growth factors, and thrombosis in PAH
۱۴. The pressure loaded right ventricle
۱۵. Genetics and genomics of PAH
۱۶. Epidemiology of PAH and PH
۱۷. Epidemiology and management of PAH in PVOD and/or PCH
۱۸. Drugs and toxins and PAH
۱۹. CTD-associated PAH
۲۰. PAH associated with HIV
۲۱. PAH associated with portal hypertension (portopulmonary hypertension)
۲۲. PAH associated with congenital systemic-to-pulmonary cardiac shunts
۲۳. PAH associated with schistosomiasis
۲۴. PAH associated with chronic haemolytic anaemias
۲۵. Haemodynamics and treatment approaches in PH due to left heart disease
۲۶. Lung disease-associated PH
۲۷. Venous thromboembolism
۲۸. Acute pulmonary embolism and investigations
۲۹. Chronic thromboembolic pulmonary hypertension
۳۰. Diagnosis and investigations in PAH
۳۱. General approach to the management of PAH
۳۲. Specific therapies for PAH