دانلود کتاب فارماکولوژی سرطان: راهنمای مصور داروهای ضد سرطان
Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs, 1ed

Cancer Pharmacology: An Illustrated Manual of Anticancer Drugs provides a one-stop guide to the essential basic and clinical science of all the effective, life-prolonging drug therapies in oncology. From traditional cytotoxic agents to targeted genomic, epigenomic, hormonal, and immunotherapeutic agents, this pharmacology book covers the staggering advances in cancer pharmacology that are propelling new standards of care for common and uncommon malignancies.

Beautifully illustrated throughout, each chapter in this cancer pharmacology guide contains visually engaging figures detailing the tumor microenvironment, chemical structures of agents, pharmacodynamics, pharmacokinetics, pharmacogenomic, and molecular properties of the various agents, and their mechanisms of action. As the first illustrated book of its kind, this highly visual text uses a uniform approach to each cancer drug class and agent presented in the book, and covers alkylating agents, antimetabolites, antimitotics, epigenetic modulators, hormonal agents, targeted therapies, monoclonal antibodies, immunotherapeutic agents, and much more.

Flow diagrams, clinical tables, and bulleted text further explain important information pertaining to each cancer drug class including their indications, mechanisms of action, potential adverse reactions, dosing and dose adjustments, and safety monitoring. Organized in an easy-to-digest format and replete with detailed images, clinical pearls, and end of chapter Q&As, this evidence-based reference presents all major classes, agents, targets, and approaches to oncology pharmacotherapy.

Contents

Chapter 1: Anticancer Drug Development: An Introduction
Chapter 2: Alkylating Agents
Chapter 3: Antimetabolites: Hydroxyurea, Pyrimidine and Purine Analogs, and L-Asparaginase
Chapter 4: Antimetabolites: Antifolates
Chapter 5: Antimitotics
Chapter 6: DMA Repair,. Apoptotic Pathways, CDK Inhibitors
Chapter 7: Epigenetic Modulators
Chapter 8: Differentiating Agents and Microenvironment
Chapter 9: Hormonal Therapies Alone and in Combinations for Treatment of Breast Cancer
Chapter 10: Male Hormonal Therapies
Chapter 11: Targeted Therapies (Small Molecules)
Chapter 12: Monoclonal Antibodies Including Immunoconjugates and Cytokine-Directed Agents
Chapter 13: Immunotherapeutics Including Vaccines, Bispecifics, CAR-T, and Checkpoint Inhibitors
Chapter 14: Multiple Myeloma as a Paradigm for Multi-Targeted Intervention
Chapter 15: Transplant-Related Agents
Chapter 16: Basic Drug Development with Structural Considerations
Chapter 17: Integral Components in Development of Clinical Trials: PK/PD, Statistics, and Principles of Rational Combinatorial Therapies
Chapter 18: Drug Approval and Regulatory Issues