دانلود کتاب تست سم شناسی ژنتیکی: راهنمای آزمایشگاهی
Genetic Toxicology Testing: A Laboratory Manual, 1ed

Genetic Toxicology Testing: A Laboratory Manual presents a practical guide to genetic toxicology testing of chemicals in a GLP environment. The most commonly used assays are described, from laboratory and test design to results analysis. In a methodical manner, individual test methods are described step-by-step, along with equipment, suggested suppliers, recipes for reagents, and evaluation criteria.

An invaluable resource in the lab, this book will help to troubleshoot any assay problems you may encounter to optimise quality and efficiency in your genetic toxicology tests. Genetic Toxicology Testing: A Laboratory Manual is an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own.

• Offers practical and consistent guidance on the most commonly-performed tests and procedures in a genetic toxicology lab
• Describes standard genetic toxicology assays, their methodology, reagents, suppliers, and analysis of their results
• Includes guidance on general approaches: formulation for in vitro assays, study monitoring, and Good Laboratory Practice (GLP)
• Serves as an essential reference for those new to the genetic toxicology laboratory, or anyone involved in setting up their own lab

About the Author

Contents

Chapter 1: A Practical Guide to Genetic Toxicology Testing
Chapter 2: General Recommendations
Chapter 3: Formulation of Test Articles
Chapter 4: The Bacterial Reverse Mutation Test
Chapter 5: The Mouse Lymphoma TK Assay
Chapter 6: The In Vitro Micronucleus Assay
Chapter 7: The In Vitro Chromosome Aberration Test
Chapter 8: The In Vivo Rodent Micronudeus Assay
Chapter 9: The Rodent Bone Marrow Chromosomal Aberration Test
Chapter 10: The In Vivo Comet Assay Test
Chapter 11: The Pig-a Endogenous Gene Mutation Assay