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Handbook of Basal Ganglia Structure and Function, 2ed

Handbook of Basal Ganglia Structure and Function, Second Edition, offers an integrated overview of the structural and functional aspects of the basal ganglia, highlighting clinical relevance. The basal ganglia, a group of forebrain nuclei interconnected with the cerebral cortex, thalamus, and brainstem, are involved in numerous brain functions, such as motor control and learning, sensorimotor integration, reward, and cognition.

These nuclei are essential for normal brain function and behavior, and their importance is further emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction.

This updated edition has been thoroughly revised to provide the most up-to-date account of this critical brain structure. Edited and authored by internationally acclaimed basal ganglia researchers, the new edition contains ten entirely new chapters that offer expanded coverage of anatomy and physiology, detailed accounts of recent advances in cellular/molecular mechanisms and cellular/physiological mechanisms, and critical, deeper insights into the behavioral and clinical aspects of basal ganglia function and dysfunction.

  • Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cellular/molecular and cellular/physiological mechanisms, and behavioral and clinical aspects of function and dysfunction
  • Written by international authors who are preeminent researchers in the field
  • Explores, in full, the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

About the Author

Heinz Steiner is Professor and Chair of the Department of Cellular and Molecular Pharmacology at the Chicago Medical School/Rosalind Franklin University of Medicine and Science in Chicago, Illinois. Dr. Steiner is an expert on the functional organization of the basal ganglia and related brain systems. His research focuses, in particular, on the role of the neurotransmitter dopamine in the regulation of basal ganglia-cortical interactions; his recent investigations examine how chronic enhancement of dopamine actions produce changes in gene regulation, and how these molecular alterations affect basal ganglia function and behavior. He has been the North America Regional Editor for the journal Basal Ganglia since 2011.

Contents

Chapter 1 The Neuroanatomical Organization of the Basal Ganglia
Chapter 2 The History of the Basal Ganglia: The Nuclei
Chapter 3 The History of the Basal Ganglia: Cells and Circuits
Chapter 4 The Conservative Evolution of the Vertebrate Basal Ganglia
Chapter 5 Cell Types in the Different Nuclei of the Basal Ganglia
Chapter 6 The Striatal Skeleton: Medium Spiny Projection Neurons and Their Lateral Connections
Chapter 7 The Cholinergic Interneuron of the Striatum
Chapter 8 GABAergic Interneurons of the Striatum
Chapter 9 Dopaminergic Modulation of Glutamatergic Signaling in Striatal Spiny Projection Neurons
Chapter 10 Endocannabinoid Signaling in the Striatum
Chapter 11 Nitric Oxide Signaling in the Striatum
Chapter 12 Role of Adenosine in the Basal Ganglia
Chapter 13 Organization of the Globus Pallidus
Chapter 14 The Subthalamic Nucleus
Chapter 15 The Substantia Nigra Pars Reticulata
Chapter 16 Subtypes of Midbrain Dopamine Neurons
Chapter 17 Neurophysiology of Substantia Nigra Dopamine Neurons: Modulation by GABA and Glutamate
Chapter 18 Plasticity in Dopamine Neurons
Chapter 19 Regulation of Extracellular Dopamine: Release and Uptake
Chapter 20 Organization of Corticostriatal Projection Neuron Types
Chapter 21 Organization of Prefrontal-Striatal Connections
Chapter 22 Gating of Cortical Input Through the Striatum
Chapter 23 Regulation of Corticostriatal Synaptic Plasticity in Physiological and Pathological Conditions
Chapter 24 The Thalamostriatal Systems in Normal and Disease States
Chapter 25 The Tail of the Ventral Tegmental Area/Rostromedial Tegmental Nucleus: A Modulator of Midbrain Dopamine Systems
Chapter 26 The Rostromedial Tegmental Nucleus: Connections With the Basal Ganglia
Chapter 27 Integrative Networks Across Basal Ganglia Circuits
Chapter 28 Receptors and Second Messengers in the Basal Ganglia
Chapter 29 Regulation of Striatal Signaling by Protein Phosphatases
Chapter 30 Neurotransmitter Regulation of Striatal Gene Expression
Chapter 31 Psychostimulant-Induced Gene Regulation in Striatal Circuits
Chapter 32 Epigenetics in Neuropathologies of the Basal Ganglia
Chapter 33 Investigating Basal Ganglia Function With Cell-Type-Specific Manipulations
Chapter 34 Phasic Dopamine Signaling in Action Selection and Reinforcement Learning
Chapter 35 Memory Systems of the Basal Ganglia
Chapter 36 Abnormal Activities in Cortico-Basal Ganglia Circuits in Movement Disorders
Chapter 37 Morphological Plasticity in the Striatum Associated With Dopamine Dysfunction
Chapter 38 Neuroinflammation in Movement Disorders
Chapter 39 Disease-Associated Changes in the Striosome and Matrix Compartments of the Dorsal Striatum
Chapter 40 Etiology and Progression of Parkinson’s Disease: Cross-Talk Between Environmental Factors and Genetic Vulnerability
Chapter 41 Determinants of Selective Vulnerability of Dopamine Neurons in Parkinson’s Disease
Chapter 42 Parkinson’s Disease: Genetics
Chapter 43 Molecular Mechanisms of l-DOPA-Induced Dyskinesia
Chapter 44 Cell Therapy in Parkinson’s Disease: Understanding the Challenge
Chapter 45 Cellular and Molecular Mechanisms of Neuronal Dysfunction in Huntington’s Disease
Chapter 46 Alterations of Synaptic Function in Huntington’s Disease
Chapter 47 Pathophysiology of Dystonia
Chapter 48 Tourette Syndrome and Tic Disorders
Chapter 49 Deep-Brain Stimulation for Neurologic and Neuropsychiatric Disorders

قیمت : 8000 تومان

لینک کوتاه : https://bookbaz.ir/?p=82949
نویسنده : Heinz Steiner , Kuei Y. Tseng
ناشر : Academic Press; 2 edition
سال انتشار : 2017
زبان کتاب : انگلیسی
نوع فایل : PDF
تعداد صفحات : 1002
(ISBN) شابک : 012802206X
قیمت کتاب درآمازون : $170.16
حجم فایل : 22 MB

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