دانلود کتاب هپاتیت ویروسی
Viral Hepatitis, 4ed

VIRAL HEPATITIS, 4^TH EDITION

Edited by Howard C. Thomas, Imperial College London, London, UK
Arie J. Zuckerman, University College London, London, UK
Anna S. F. Lok, University of Michigan Health System, Ann Arbor, MI, USA
Stephen A. Locarnini, Victorian Infectious Diseases Reference Laboratory, Melbourne, VIC, Australia

The 4^th edition of Viral Hepatitis covers comprehensively the entire complex field of infections caused by all of the different hepatitis viruses, which affect many millions of people throughout the world with considerable morbidity and mortality.

Howard Thomas and Arie Zuckerman are joined by Anna Lok from the USA and Stephen Locarnini from Australia as Editors.  They have recruited leading researchers and physicians from many countries, who have produced an authoritative account of current knowledge and research on this important infection, including new insights into immune response to HBV and HCV.

The result is a comprehensive account on all aspects of viral hepatitis, including rapid advances in the diagnosis, management, treatment and prevention of a complex infection, which in the case of hepatitis B, C and D may lead to severe complications including chronic hepatitis, cirrhosis and hepatocellular carcinoma.

The latest edition of Viral Hepatitis offers an essential resource of current information for hepatologists, gastroenterologists, infectious diseases specialists and other clinicians, researchers, public health physicians and National and International Health Authorities.

Contents

Section I: Introduction to Liver Biology

۱ Liver regeneration and fibrosis 3
۲ Hepatic immunology 13

Section II: Hepatitis A Virus

۳ Structure molecular virology natural history and experimental models 29
۴ Epidemiology and prevention 43

Section III: Hepatitis B Virus and Other Hepadnaviridae

۵ Structure and molecular virology 65
۶ Epidemiology and prevention 81
۷ Other Hepadnaviridae (including Avihepadnaviridae and woodchuck hepatitis viruses) 96
۸ Molecular variants of hepatitis B surface antigen (HBsAg) 107
۹ Molecular variants of the precore core and core promoter regions of hepatitis B virus and their clinical significance 127
۱۰ Natural history of chronic hepatitis B virus infection 143
۱۱ Extrahepatic manifestations of hepatitis B infection 154
۱۲ Hepatocellular carcinoma: Molecular aspects in hepatitis B 163
۱۳ Murine models and human studies of pathogenesis of chronic hepatitis B 176
۱۴ Treatment of hepatitis B 188
۱۵ Liver transplantation for chronic hepatitis B and C 203

Section IV: Hepatitis C Virus

۱۶ Structure and molecular virology 221
۱۷ Epidemiology and prevention 246
۱۸ The immune response to HCV in acute and chronic infection 266
۱۹ Animal models of hepatitis C virus infection 280
۲۰ Extrahepatic manifestations of hepatitis C virus infection 295
۲۱ Central nervous system complications of hepatitis C virus infection 310
۲۲ In vitro replication models 325
۲۳ Natural history of chronic HCV infection and non-invasive assessment of hepatic fibrosis 341
۲۴ Hepatitis C and hepatocellular carcinoma 353
۲۵ Treatment of hepatitis C 362
۲۶ Development of anti-HCV drugs 377

Section V: Hepatitis D Virus

۲۷ Structure and molecular virology 395
۲۸ Epidemiology and natural history 403
۲۹ Treatment of hepatitis D 410

Section VI: Hepatitis E Virus

۳۰ Structure and molecular virology 419
۳۱ Epidemiology experimental models and prevention: zoonotic aspects of hepatitis E 431
۳۲ Clinical and pathological features and diagnosis 442

Section VII: Clinical Aspects of Viral Liver Disease

۳۳ Clinical and diagnostic aspects of viral hepatitis 453
۳۴ Treatment of acute hepatitis severe acute hepatitis and acute liver failure 468
۳۵ Hepatitis and hemophilia 486
۳۶ Hepatitis in persons infected with HIV 494
۳۷ Migration hepatitis B and hepatitis C 506
۳۸ Occupational aspects of hepatitis 515
۳۹ Neonatal and pediatric infection 529
۴۰ Management of hepatocellular carcinoma 544
۴۱ Application of molecular biology to the diagnosis of viral hepatitis 552
۴۲ Disinfection and sterilization 564
۴۳ Evolution of hepatitis viruses 575