دانلود کتاب شیمی تصویربرداری مولکولی
The Chemistry of Molecular Imaging, 1ed

The first book to apply the chemistry perspective to imaging techniques and their applications

The development of a plethora of bioimaging techniques, such as the MRI, PET, SPECT, ultrasound and optical/fluorescence imaging, has been vital to improving human life. Although these imaging technologies continue to advance with unique applications and advantages, the ability to see within the human body and understand its biological complexities remains one of the greatest challenges of modern medical science. The Chemistry of Molecular Imaging is the first book written from a chemist’s point of view about the chemistry of novel biological probes, addressing the nature of the chemical interaction between probe and environment to help elucidate biochemical detail instead of bulk anatomy.

Written by experts of various fields and aimed at students as well as researchers involved in the area of molecular imaging, this book:

• Covers all of the fundamentals of modern imaging methodologies, including their techniques and application within medicine and industry
• Focuses primarily on the chemistry of probes and imaging agents, and chemical methodology for labelling and bioconjugation
• Investigates the chemistry of molecular imaging and helps to educate non-chemists already involved in the area of molecular imaging
• Addresses all applications and techniques, including MRI, positron emission tomography, single photon emission computed tomography, ultrasound, and fluorescence/optical imaging

Consisting of sixteen chapters, with examples and illustrations, the book constructs a comprehensive picture of imaging chemistry, from introducing the various imaging modes, to investigating the nature and properties of multi-modality imaging contrast agents. Thus, readers, including synthetic chemists, undergraduate or graduate students, educators, and medical professionals in the field, will gain a thorough understanding of the art of imaging contrast agent design.

Nicholas Long, PhD, is the Sir Edward Frankland BP Professor of Inorganic Chemistry and Head of the Catalysis, Sustainability and Applied Inorganics section in the Department of Chemistry, Imperial College London. He has published more than 150 scientific papers, including several high impact review articles and a critically-acclaimed textbook titled ‘Metallocenes’. He is Co-Director of the Centre for Doctoral Training in Medical Imaging at Imperial College and King’s College London.

Wing-Tak Wong, PhD, ScD, is Chair Professor of Chemical Technology and Head of the Department of Applied Biology and Chemical Technology at the Hong Kong Polytechnic University. He has received three International and US patents for his recent research on lanthanide luminescent materials, and is an author of more than 450 research papers.

Review

Contents

Chapter 1 An Introduction to Molecular Imaging
Chapter 2 Chemical Methodology for Labelling and Bioconjugation
Chapter 3 Recent Developments in the Chemistry of [ieF]Fluoride for PET
Chapter 4 Carbon-11, Nitrogen-13,and Oxygen-15 Chemistry: An Introduction to Chemistry with Short-Lived Radioisotopes
Chapter 5 The Chemistry of Inorganic Nuclides {86Y, 68Ga, 64Cu, 89Zr, 1241}
Chapter 6 The Radiopharmaceutical Chemistry of Technetium and Rhenium
Chapter 7 The Radiopharmaceutical Chemistry of Gallium[III) and Indium[III} for SPECT Imaging
Chapter 8 The Chemistry of Lanthanide MRI Contrast Agents
Chapter 9 Nanoparticulate MRI Contrast Agents
Chapter 10 CEST and PARACEST Agents for Molecular Imaging
Chapter 11 Organic Molecules for Optical Imaging
Chapter 12 Application of d- and f-Block Fluorescent Cell Imaging Agents
Chapter 13 Lanthanide-Based Upconversion Nanophosphors for Bioimaging
Chapter 14 Microbubbles: Contrast Agents for Ultrasound and MRI
Chapter 15 Non-Nanoparticle-Based Dual-Modality Imaging Agents
Chapter 16 Chemical Strategies for the Development of Multimodal Imaging Probes Using Nanoparticles