دانلود کتاب اصول پزشکی خاص جنسیتی
Principles of Gender-Specific Medicine, 4ed

Awarded with the 2018 Prose Award in Clinical Medicine, the third edition of Principles of Gender-Specific Medicine explored and described exciting new areas in biomedicine that integrated technology into the treatment of disease and the augmentation of human function. Novel topics such as the sex-specific aspects of space medicine, the development and the use of genderized robots and a discussion of cyborgs were included in the third edition, providing a preview of the expanding world of sex-specific physiology and therapeutics. This Fourth Edition is a continuation of the mission to trace the relevance of biological sex to normal function and to the experience of disease in humans.

We are now twenty years into the postgenomic era. The investigation of how the genome produces the phenome has led to fascinating insights as well as yet unanswered questions. Principles of Gender-Specific Medicine, Fourth Edition, has a central theme: discuss advances in understanding the role of epigenetics in regulating gene expression in a dynamic, sex-specific way during human life. It explores the protean role of epigenetics in human physiology, the relevance of environmental experience to human function, the therapeutic promise of cutting-edge methodologies like gene manipulation, the preparation of humans for space travel, the use of artificial intelligence in detection and therapeutic decisions concerning disease states, the possibilities for technological support of not only compromised individuals but of the augmentation of human function, and an analysis of the benefits, limitations and issues that surround our current expectations of personalized medicine.

  • Covers the most important developments in biomedical research in the past decade, with a thoughtful analysis of how they impact patient care
  • Discusses the feasibility and usefulness of personalized medicine, the limits and promise of genetic editing, the basis for variation in sexual identity and how artificial intelligence and technology will affect basic human function as well as correcting disability
  • Promotes and facilitates discussions about the ethics and governance issues that surround much of what science is now able to do at the most basic levels of human’s physiology

Review

Discusses the relationship of biological sex to human function and why it is relevant to the new diagnostic and therapeutic modalities currently being developed as a result of postgenomic research.

Contents

۱. Is there a role for natural selection in sex differences?
۲. Spermatozoa selection in the female reproductive tract: The initiation of the battle of the sexes
۳. Gender/sex: Shaping identity in infancy and early childhood
۴. A gendered brain perspective from structure to brain interactions
۵. Sex-specific implications of exposure to an adverse intrauterine environment
۶. Mate choice and the genetic imprint of the battle of the sexes
۷. Using the exposome to understand the role of the environment in gender- and sex-specific medicine
۸. Regulation of gene expression in the brain by sex hormones
۹. Sex-specific differences in mitochondrial function and its role in health disparities
۱۰. Sex differences in fetal programming: Antenatal origins of health and disease (AOHD)
۱۱. Sex differences in the brain: Focus on developmental mechanisms
۱۲. Genes, environments, and epigenetics
۱۳. Epigenetics: Mechanisms, theory, and social implications
۱۴. Adipose-derived stem cells: Use in clinical medicine
۱۵. All cells have a sex: Sex chromosome function at the cellular level
۱۶. Best-laid plans: The establishment of biological sex and its susceptibility to genetic and environmental disruption
۱۷. CRISPR technology and its potential role in treating rare imprinting diseases
۱۸. Parental genome and brain functions: The case of genomic imprinting
۱۹. Microbiome: Impact of sex on function and characteristics of gut microbiome
۲۰. Geoepidemiology and the key role of sex chromosomes on autoimmune diseases
۲۱. Molecular mechanisms of sex differences in epilepsy
۲۲. Consideration of biological sex in stem cell therapies
۲۳. Sex and the human brain: Moving beyond the binary
۲۴. Genomic and epigenomic signature at the branch-point among genome, phenome, and sexome in health and disease: A multiomics approach
۲۵. The importance of gender-specific medicine in the pharmaceutical industry, clinical practice, and global health care
۲۶. The neurobiology of gender identity and gender dysphoria
۲۷. Nutritional genomics and biological sex
۲۸. The invaluable contribution of animal models in understanding sex-dependent differences in neuropsychiatric disorders
۲۹. Sexual dimorphism in molecular biology of cancer
۳۰. The importance of expeditionary fitness in optimizing the human commercial spaceflight experience
۳۱. Brain morphological changes associated with sexual orientation
۳۲. The operationalization of gender in medicine
۳۳. Precision medicine: Overview and challenges to clinical implementation
۳۴. Assessment of fall risks in older females and males using an automated smartphone mobility suite
۳۵. Statin therapy and sex hormones
۳۶. Exercise physiology in women and men
۳۷. Cerebral effects of gender-affirming hormone treatments in transgender persons
۳۸. Artificial intelligence in healthcare
۳۹. Trauma and gender in primary care
۴۰. Fertility treatment and preservation in transgender men and women
۴۱. Atrial fibrillation in women
۴۲. Sex differences in COVID-19 susceptibility – Reductionistic and holistic perspectives
۴۳. Sex and gender differences in sleep disorders: An overview
۴۴. Estrogen: Impact on cardiomyocytes and the heart
۴۵. Beyond sex and gender differences: The case for women’s health research
۴۶. Measurement and meaning of gender/sex from bench to bedside – And the mutuality of equity and precision in medicine
۴۷. Person-centered cancer genetic counseling for transgender and gender diverse patients
۴۸. Musculoskeletal complaints in male and female instrumental musicians
۴۹. Sex, gender, and pain
۵۰. Influence of gender on the pathophysiology and treatment of urological malignancies
۵۱. Beyond the mask: The role of camouflaging in managing an autistic identity for girls and women
۵۲. There is no stronger sex: Evolutionary Anthropology’s conclusion based on the sex-typical susceptibility to stress factors during prenatal development
۵۳. Robots and gender
۵۴. Sex specificity in neonatal diseases
۵۵. Human male and female phenotypes depend on lifestyle (smoking and hormonal contraceptives): Implications for prevention and care

قیمت : 60000 تومان

لینک کوتاه : https://bookbaz.ir/?p=403617
نویسنده : Marianne Legato J M.D. PhD
ناشر : Academic Press; 4th edition
سال انتشار : 2023
زبان کتاب : انگلیسی
نوع فایل : PDF (نسخه اصلی)
تعداد صفحات : 909
(ISBN) شابک : 0323885349
قیمت کتاب درآمازون : $136.45
حجم فایل : 45 MB

۶۰۰۰۰ تـومان – خرید