دانلود کتاب راهنمای کلسترول: زیست شناسی، عملکرد و نقش در سلامت و بیماریها
Handbook of Cholesterol: Biology, Function and Role in Health and Diseases, 1ed

The handbook of cholesterol – biology, function and role in health and disease – gathers a substantial set of contributions supporting the modern view that dietary and blood cholesterols are safe or even beneficial in a balanced omega-6/3 fatty acids environment, whereas they may turn into unsafe or detrimental to health in a typical omega-6 fatty acid environment. Dietary and blood cholesterols, including LDL-cholesterol, are secondary risk factors which belong to the human omnivorous diet and physiology, which may represent clinical valid surrogates of the outcome, cardiovascular diseases. However, the primary risk factors, the omega-6/3 fatty acids, determine whether human health is in the safe evolutionary zone or not. Omega-6/3 fatty acids are essential to human physiology. They must be present and maintained in physiologically-defined essential amounts and balanced in blood and tissue lipid pools, through the diet. Chronic deviations from omega-6/3 fatty acids make LDL-cholesterol valid indicators of cardiovascular disease. The handbook takes preventive and acute approaches, based on biochemical and clinical evidence, to the management of cholesterol – a per se non-essential nutrient, yet an essential blood and tissue component. The reviews, especially when combined, will help understand the essentiality of dietary and blood cholesterol as (risk) factors in human health.

Contents

۱. Hypercholesterolemia: a disease of the brain
۲. Cholesterol and cognitive functioning in persons free from stroke and dementia
۳. The role of cholesterol in disorders of brain and behavior: human and animal perspectives
۴. Macrophage deposition of extracellular lipid particles with microdomains of ordered cholesterol arrays
۵. Cellular cholesterol retention in atherosclerosis and direct anti-atherosclerosis therapy
۶. Dietary cholesterol and the lack of evidence on heart disease risk
۷. Cholesterol: the most misunderstood marker
۸. Sphingosine-l-phosphate-rich high-density lipoprotein in cardiovascular health and disease
۹. Statins in the treatment and prevention of cardiovascular diseases
۱۰. Cholesterol content and health effects in free range, organic and conventionally raised poultry and eggs
۱۱. Cholesterol and fatty acid content and health effects in grass-fed and conventionally raised grain-fed beef
۱۲. Some chronobiological investigations relevant to cholesterol
۱۳. Cholesterol and the etiology of malaria
۱۴. Familial hypercholesterolemia
۱۵. Cholesterol-containing foods for children and adolescents: recommendations catching up with research
۱۶. The relationship between cholesterol metabolism and inflammation in chronic disease
۱۷. Cellular cholesterol retention in atherosclerosis
۱۸. Polyunsaturated fatty acids, cholesterol, triglycerides and cardiometabolic disease
۱۹. Cholesterol: chemistry, cancer metabolism and tumorigenesis
۲۰. Bariatric surgery for modified cholesterol metabolism
۲۱. Why measuring cholesterol is obsolete and costly
۲۲. Egg yolk cholesterol and its functions in human health
۲۳. The eggs and cholesterol: a liability or an opportunity?
۲۴. Cholesterol and vitamin D: how the ‘mother’ and ‘daughter’ molecules interact
۲۵. Antioxidant system regulation: from vitamins to vitagenes